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Theses/Dissertations from 2021

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Protein Conformational Stability Enhancement Through PEGylation and Macrocyclization, Qiang Xiao

Theses/Dissertations from 2020

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Microfabricated Fluidic Devices for Biological Assays and Bioelectronics, Anna V. Bickham

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Discovery of a Novel Regulatory Mechanism of TNK1 by 14-3-3 and Its Ubiquitin Association Domain Provides a Potential Therapeutic Targeting Opportunity in Cancer, Tsz Yin Chan

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Organic Synthesis using Bimetallic Catalysis, Chloe Christine Ence

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Instrumentation and Application of Image-Charge Detection of Electrospray-Charged Microparticles and Microdroplets, Jiuzhi Gao

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Synthesis of Functionalized Streptococcus pneumoniae Serotype 6A Di- and Tri- Saccharides, Brady Davis James

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An ULK1-Independent Mechanism of ATG9A Regulation in Basal Autophagy, Ashari Rashmi Kannangara

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Breaking the Organic Mold: Introducing Copper into the Influenza A Arena with Neutral and Divalent Complexes, Jonathan D. Lynch

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Galectin-1 Improves Sarcolemma Repair and Decreases the Inflammatory Response in LGMD2B Models, Matthew F. Rathgeber

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Thin Film Deposition on Powder Substrates using ALD and its Characterization using XPS, TEM, and SE, Dhruv Shah

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Structures and Characteristics of Macromolecular Interactions in Gas Phase Using Fourier-Transform Ion Cyclotron Resonance Mass Spectrometry, Jiewen Shen

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The Role of the Chaperone CCT in Assembling Cell Signaling Complexes, Nicole C. Tensmeyer

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Capillary Morphogenesis Gene Protein 2 (CMG2) Mediates Matrix Protein Uptake and is Required for Endothelial Cell Chemotaxis in Response to Multiple Vascular Growth Factors, Tsz Ming Jeremy Tsang

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Design, Synthesis, and Characterization of New Non-Centrosymmetric Organic Crystals for Terahertz Generation, Gabriel Alejandro Valdivia-Berroeta

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Novel αvβ6 Inhibitor Reduces Fibrotic Progression in Idiopathic Pulmonary Fibrosis Murine Model, Rebecca C. Viazzo Winegar

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The Investigation of Functionalized Carbon Nanotubes for the Carbon Dioxide Capture and Ethane Oxidative Dehyrogenation Catalysts, Zheng Zhou

Theses/Dissertations from 2019

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3D Printed Microfluidic Devices for Bioanalysis, Michael J. Beauchamp

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The Investigation of Secondary Particle Formation Initiated by Non-Prototypical Sources and the role of Amines in the Atmosphere, Emily Burrell

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Inclusion of Kinetic Proteomics in Multi-Omics Methods to Analyze Calorie Restriction Effects on Aging, Richard Hajime Carson

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Applications of Pattern Recognition Entropy (PRE) and Informatics to Data Analysis, Shiladitya Chatterjee

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Multi-Instrument Surface Characterization of Display Glass, Cody Vic Cushman

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DNA Capture via Magnetic Beads in a Microfluidic Platformfor Rapid Detection of Antibiotic Resistance Genes, David Hyrum Harris

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Preparation, Functionalization, and/or Characterization by X-ray Photoelectron Spectroscopy of Carbon Surfaces for Biosensors and Other Materials, Varun Jain

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Preparation and Detailed X-Ray Photoelectron Spectroscopy and Spectroscopic EllipsometryAnalysis of Ultrathin Protective Coatings, Brian Ivins Johnson

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Computational Studies of High-Oxidation State Main-Group Metal Hydrocarbon C-H Functionalization, Clinton R. King

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Bifunctional Helical Peptide Catalysts for Enzyme-like Reactivity and Selectivity and Selective Stapling of Natural Amino Acid Residues with Hydrophilic Squaric Acid Derivatives, Michael James Kinghorn

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Computational Design and Analysis of Molecular Ethylene Oligomerization Catalysts, Doo Hyun Kwon

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Design and Synthesis of Ceragenins–Cationic Steroid Antimicrobial Compounds, Structural Improvement and Synthesis of Cyclopentenone Prostaglandins and Modification and Synthesis of Derivatives of Ribityllumazines: Potential Antigens for Activation of MAIT Cells, Yubo Li

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Design and Synthesis of TLR2 and TLR6 Heterodimer Ligands, a Triply Functionalized α-GalCer Derivative for Identifying Proteins Involved in Glycolipid Trafficking, and the Disaccharide of Staphylococcus aureus CP8 Towards a Self-Adjuvanting Vaccine, Sara Mayeth Mata

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Antibacterial and Antifungal Activity of Ceragenins, Mimics of Endogenous Antimicrobial Peptides, Marjan Mohammadihashemi

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Selective Catalysis by Polymer-Supported Ruthenium NanoparticlesAND New Ligand Design for Cooperative and Bimetallic Catalysis, Seyed Hadi Nazari

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The Investigation of Nickel-Based Catalysts for the Oxidative Dehydrogenation of Ethane, Justin Lane Park

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Exploration of Sputtered Thin Films—E.g., in Sample Preparation and Material Characterization, Tuhin Roychowdhury

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Total Synthesis of Anticancer Agent Deoxypodophyllotoxin and Antiviral F4-4 Demonstrating the Utility of the Intramolecular Styryl Diels-Alder (ISDA) Reaction, Diana Isabel Saavedra Nova

Theses/Dissertations from 2018

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An Introductory Study of Solid Materials for Capture and Catalysis of Waste Stream Chemicals, Steven Kyle Butler

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Endocytosis as an Additional Mechanism of Glucose Transport to the Hexose Transporter in Trypanosoma brucei, JongSu Choi

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Fluorescent Labeling of Antibiotic Resistant Bacteria Model DNA, Janice Darko

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The Use Of Tissue And Serum ”˜Omics' Methods To Characterize Disease, Ying Ding

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Contribution of Bulky <&alpha>,<&beta>-Dehydroamino Acids to the Proteolytic Stability andEnhanced Folding of <&beta>-Hairpins and Progress Towards the Total Synthesis of Yaku<'>amide A, Ankur Jalan

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Creation and Use of Software for Analysis of Kinetic Proteomic Experiments, Bradley C. Naylor

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Development of Affinity Monoliths in 3D Printed Microfluidic Devices for Extraction of Preterm Birth Biomarkers, Ellen Kelsey Parker

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Application of the Entropy Concept to Thermodynamics and Life Sciences: Evolution Parallels Thermodynamics, Cellulose Hydrolysis Thermodynamics, and Ordered and Disordered Vacancies Thermodynamics, Marko Popovic

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Measuring the Interaction and Cooperativity Between Ionic, Aromatic, and Nonpolar Amino Acids in Protein Structure, Mason Scott Smith

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Development and Use of Lipidomics and Proteomics Methods to Identify and Measure Pro-Survival Metabolic Pathways in Cancer, Monique Merilyn Speirs

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Synthesis and Determination of the Local Structure and Phase Evolution of Unique Boehmite-Derived Mesoporous Doped Aluminas, Ying Zhang

Theses/Dissertations from 2017

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Advancements in the Understanding of Nonlinear Optics and Their Use in Material Analysis, Shawn C. Averett

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Post-Translational Regulation of Superoxide Dismutase 1 (SOD1): The Effect of K122 Acylation on SOD1's Metabolic Activity, Courtney Jean Banks

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Microwave-Promoted Iminyl Radical Cyclizations for the Synthesis of Azaheterocycles and the Total Synthesis of Yaku'amide A, Yu Cai

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Role of Molecular Chaperonin CCT and Its Co-Chaperone PhLP1 in the Assembly of mTOR Complexes, Madhura Vinayak Dhavale

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Fundamental Studies and Applications of Ambient Plasma Ionization Sources for Mass Spectrometry, Wade C. Ellis

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Anthrax, Matrix Biology, and Angiogenesis: Capillary Morphogenesis Gene 2 Mediates Activity and Uptake of Type IV Collagen-Derived Anti-Angiogenic Peptides, Jordan Grant Finnell

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Ion Trajectory Simulations and Design Optimization of Toroidal Ion Trap Mass Spectrometers, Jessica Marie Higgs

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Microwave-Promoted Iminyl Radical Fragmentations: A Practical and Efficient Method of Functionalization, Mary Megan Jackman

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Ion Transport in a Commercial ICP-MS, Jessica Joline Larsen

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Desorption Electrospray Ionization (DESI) Mass Spectrometric Imaging of Spatially Regulated In Vivo Metabolic Rates, Charlotte Reininger Lewis

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Miniaturization of Linear Ion Traps and Ion Motion Study in a Toroidal Ion Trap Mass Analyzer, Ailin Li

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Capacity of Human Immunodeficiency Virus Targeting Chimeric Antigen Receptor T Cells to Eliminate Follicular Dendritic Cells Bearing Human Immunodeficiency Virus Immune Complexes, Matthew T. Ollerton

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Capacity of Human Immunodeficiency Virus Targeting Chimeric Antigen Receptor T Cells to Eliminate Follicular Dendritic Cells Bearing Human Immunodeficiency Virus Immune Complexes, Matthew T. Ollerton

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Acylation of Superoxide Dismutase 1 (SOD1) at K122 Alters SOD1 Localization and SOD1-Mediated Inhibition of Mitochondrial Respiration, Nathan William Rodriguez

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Semiconductor Terahertz Electronics and Novel High-Speed Single-Shot Measurements, Parker Dean Salmans

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Electrokinetically Operated Integrated Microfluidic Devices for Preterm Birth Biomarker Analysis, Mukul Sonker

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Ion Trap Miniaturization Considerations: Space-Charge Effects in Cylindrical Ion Traps and Misalignment Effects in a Two-Plate Linear Ion Trap, Yuan Tian

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Electrophilic Catalysis Using Heterobimetallic Complexes, Whitney Kaye Walker

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Functional and Mechanistic Insight into the Role of ATG9A in Autophagy, Vajira Kaushalya Weerasekara

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Enzyme Encapsulation, Biosensing Endocrine Disrupting Chemicals, and Bio-therapeutic Expression Platforms Using Cell-Free Protein Synthesis, Seung Ook Yang

Theses/Dissertations from 2016

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Discovery of Low-Molecular Weight Novel Serum Biomarkers for Diagnosing Preeclampsia and Alzheimer's Disease, Swati Anand

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Gas Phase Structure Characterization Using Fourier Transform Ion Cyclotron Resonance Mass Spectrometry, Anupriya Anupriya

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Structural Analysis of Cell Signaling Complexes, Takuma Aoba

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Determination of Fine Particulate Matter Composition and Development of the Organic Aerosol Monitor, Paul Michael Cropper

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Novel Sputtered Stationary Phases for Solid Phase Microextraction, and Other Coatings and Materials for Surface Applications, Anubhav Diwan

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Computational Studies on Mechanisms and Reactivity of Mercury and Cobalt Organometallic Reactions, Jack Terrell Fuller

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Computational Studies of Alkane C-H Functionalization by Main-Group Metals, Samantha Jane Gustafson

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Role for Reactive Oxygen Species in Methamphetamine Modulation of Dopamine Release in the Striatum, David Matthew Hedges

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Analyses of mRNA Cleavage by RelE and the Role of tRNA Methyltransferase TrmD Using Bacterial Ribosome Profiling, Jae Yeon Hwang

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14-3-3ζ Regulation of Metastasis Through Mediation of Liprin-α and Liprin-β, Rachel Hynes

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Studies Toward Yaku'amide A and Synthesis and Applications of Bulky α,β-Dehydroamino Acids, Jintao Jiang

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Placental ‘€˜Omics’€™ Study to Understand the Pathogenesis of Preeclampsia, Komal Kedia

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Criteria for Selecting PEGylation Sites on Proteins for Higher Thermodynamic Stability, Paul B. Lawrence

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Synthesis and Biological Evaluation of Small Molecule Inhibitors of BMPR1b, Paulo Andre Machicao Tello

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Control of Matrix Metalloproteinases in a Periodontitis Model: Molecules That Trigger or Inhibit MMP Production, Catalina Matias Orozco

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Glutamic Acid Resorcinarene-based Molecules and Their Application in Developing New Stationary Phases in Ion Chromatography, Tayyebeh Panahi

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Development and Application of New Solid-State Models for Low-Energy Vibrations, Lattice Defects, Entropies of Mixing, and Magnetic Properties, Jacob M. Schliesser

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Investigation of Dynamic Biological Systems Using Direct Injection and Liquid Chromatography Mass Spectrometry, Adam Clayton Swensen

Theses/Dissertations from 2015

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Image-Charge Detection – Novel Instrumentation and Applications, Brandon Lee Barney

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A Study of Allylic Aminations as Catalyzed by Heterobimetallic Pd-Ti Complexes, Diana Lauren Ellis

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Synthesis and Characterization of Carbonized Poly (Divinylbenzene) Microspheres for Carbon/Nanodiamond/Polymer-Based Core-Shell Materials and Applications of This Mixed-Mode Phase to High-Performance Liquid Chromatography, Chuan-Hsi Hung

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Mass Spectrometry Based Proteomics and Lipidomics Studies, Huan Kang

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Analytical Approaches in Investigating the Kinetics of Water-Molecule Complexes in Tropospheric Reactions, William J. Keeton

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Design, Fabrication, and Optimization of Miniaturized Devices for Bioanalytical Applications, Suresh Kumar

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Peroxy Radical - Water Complexes: Their Role in the Atmosphere, Sambhav Rajendra Kumbhani

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Studies on the Roles of Translationally Recoded Proteins from Cyclooxygenase-1 and Nucleobindin Genes in Autophagy, Jonathan J. Lee

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Ribosome Component Turnover Kinetics Describes a Two-Pool Kinetic Model in Dietary Restriction that Suggests RPL10 is Exchanged During Ribosome Lifespan, Andrew David Mathis

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Progress Towards the Total Synthesis of Yaku'amide A, Zhiwei Ma

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DNA Origami Stabilized and Seeded with 4'-Aminomethyltrioxsalen for Improved DNA Nanowire Fabrication, Matthew Paul McDowell

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Histone Deacetylase 6 (HDAC6) Is Critical for Tumor Cell Survival and Promotes the Pro-Survival Activity of 14-3-3ζ viaDeacetylation of Lysines Within the14-3-3ζ Binding Pocket, Jeffrey Benjamin Mortenson

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Fluorescence Imaging of Analyte Profiles in an Inductively Coupled Plasma with Laser Ablation as a Sample Introduction Source, Lance Moses

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Immunoassays of Potential Cancer Biomarkers in Microfluidic Devices, Jayson Virola Pagaduan

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Optimization of Nonadsorptive Polymerized Polyethylene Glycol Diacrylate as a Material for Microfluidics and Sensor Integration, Chad Rogers

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Hand-portable Capillary Liquid Chromatography Instrumentation, Sonika Sharma

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Advanced Data Analysis Tools and Multi-Instrument Material Characterization, Bhupinder Singh