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Theses/Dissertations from 2022

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Gas Phase Techniques for the Study of Biomolecular and Supramolecular Structures and Chemistry, Andrew J. Arslanian

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Identification of Sources of Air Pollution Using Novel Analytical Techniques and Instruments, Nitish Bhardwaj

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Experimental Design and Construction of the First Rotor Induced Collision Cell (RICC) for Studying High Velocity Molecular Impacts, Abraham Lehi De la Cruz Hernandez

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Understanding the Complexities of Anemia in Chronic Inflammatory Diseases from Diagnosis to Treatment, Naomi Rae Flindt

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Development of Cooperative Catalytic Systems and Bimetallic Catalysts for Organic Synthesis, Kelton Guy Forson

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Atomic Layer Deposition and High Sensitivity-Low Energy Ion Scattering for the Determination of the Surface Silanol Density on Glass and Unsupervised Exploratory Data Analysis with Summary Statistics and Other Methods, Tahereh Gholian Avval

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Charge Detection Mass Spectrometry Using Printed Circuit Board Arrays for the Analysis of Microparticles in the Martian Atmosphere, Elaura LuAnne Gustafson

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Ion Structure Characterization and Energetics in the Gas Phase Using Fourier Transform Ion Cyclotron Resonance Mass Spectrometry and Ion Mobility Spectrometry, Tina Heravi

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Synthesis of Yaku’amide A Analogues and Impact of Dehydroamino Acids on the Structure and Stability of Incipient 310 Helical Peptides, Daniel Joaquin

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Inhibition of Cell Adhesion and Actin Localization During Migration Upon Protective Antigen Mutant Ligand Binding to the Capillary Morphogenesis Gene 2, Sai Lun Lee

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Quantifying Protein Quality to Understand Protein Homeostasis, Hsien-Jung Lavender Lin

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A Machine Learning Approach that Integrates Clinical Data and PTM Proteomics Identifies a Mechanism of ACK1 Activation and Stabilization in Cancer, Eranga Roshan Balasooriya Loku Balasooriyage

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The Discovery of Novel 14-3-3 Binding Proteins ATG9A and PTOV1 and Their Role in Regulating Cancer Mechanisms, Colten Mitchell McEwan

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Synthesis and Applications of α,β-Dehydroamino Acid-Containing Peptides, Diego A. Moya

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ATG9A and ATG13 Cooperate to Drive Basal Autophagy, Daniel Morgan Poole

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Material Characterization Using Nuclear Magnetic Resonance, Giovanna Marcella Pope

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Fabrication and Characterization of DNA Templated Electronic Nanomaterials and Their Directed Placement by Self-Assembly of Block Copolymers, Dulashani Ruwanthika Ranasinghe Weerakkodige

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Gas Phase Structure Characterization of Host-Guest Systems Using Ion Mobility Spectrometry, Jamir Shrestha

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High-Velocity Impact Dissociation of Molecular Species in Spacecraft-Based Mass Spectrometers, Brandon M. Turner

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Computationally Assisted NMR Crystallography: A Path to Unusually High-Resolution Crystal Structures, Luther Wang

Theses/Dissertations from 2021

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Immunoaffinity Monoliths for Multiplexed Extraction of Preterm Birth Biomarkers from Human Blood Serum in 3D Printed Microfluidic Devices, Haifa Mohammad Almughamsi

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Bottom-Up Fabrication and Characterization of DNA Origami-Templated Electronic Nanomaterials, Basu Ram Aryal

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The Mechanism of PTOV1 Regulation by 14-3-3, HUWEI1 and SGK2, Pramoda Sahan Kumari Aththota Gamage

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Molecular Dynamics of Organometallic Systems, Ryan Wayne Carlsen

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PEGylation Stabilizes the Conformation of Proteins and the Noncovalent Interactions Within Them, Steven R. E. Draper

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Going for Gold: Point of Care Bio-Diagnostics and Gold Nanoparticles Treating Disease, Trevor M. Godfrey

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Sequence Specific Concentration and Labeling of Bacterial Plasmids for Future Use in Detection of Drug-Resistant Sepsis Cases Without Amplification, Robert L. Hanson

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Cationic Steroid Antimicrobials: Applications to Medical Device Coatings, Mechanism of Pro-Osteogenic Properties, and Potential Synergy with Common Antifungals, Brian J. Hilton

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Nonlinear Ultrafast Excitation and Two-Dimensional Terahertz Spectroscopy of Solids, Brittany E. Knighton

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Microwave-Promoted Iminyl Radical Fragmentations and the Total Synthesis of Yaku'amide A and its Simplified Analogues, Concordia Lo

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The Role of the Cytosolic Chaperonin CCT in Folding β-Propeller Proteins, William Grant Ludlam

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2-Phosphinoimidazole Derived Monometallic and Bimetallic Catalysts, Erin Martinez

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Non-Linear Optical Characterization of Stressed Materials, Kaylee N. Rellaford

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Electrocatalytic Oxidation of Carbohydrates Via Surface Immobilized Viologen, Dallin D.V. Scott

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Synthesis and Biological Evaluation of Pyrazolo[1,5-a]pyrimidines and (4-Hydroxy-6-trifluoromethylpyrimidin-2-yl) guanidines, Justin Dave Singleton

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Synthesis and Utility of Chiral and Achiral Trifluoroacetamide Substrates in Cycloaddition Reactions, Isaac Theodore Smith

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Protein Conformational Stability Enhancement Through PEGylation and Macrocyclization, Qiang Xiao

Theses/Dissertations from 2020

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Microfabricated Fluidic Devices for Biological Assays and Bioelectronics, Anna V. Bickham

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Discovery of a Novel Regulatory Mechanism of TNK1 by 14-3-3 and Its Ubiquitin Association Domain Provides a Potential Therapeutic Targeting Opportunity in Cancer, Tsz Yin Chan

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Organic Synthesis using Bimetallic Catalysis, Chloe Christine Ence

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Instrumentation and Application of Image-Charge Detection of Electrospray-Charged Microparticles and Microdroplets, Jiuzhi Gao

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Synthesis of Functionalized Streptococcus pneumoniae Serotype 6A Di- and Tri- Saccharides, Brady Davis James

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An ULK1-Independent Mechanism of ATG9A Regulation in Basal Autophagy, Ashari Rashmi Kannangara

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Breaking the Organic Mold: Introducing Copper into the Influenza A Arena with Neutral and Divalent Complexes, Jonathan D. Lynch

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Galectin-1 Improves Sarcolemma Repair and Decreases the Inflammatory Response in LGMD2B Models, Matthew F. Rathgeber

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Thin Film Deposition on Powder Substrates using ALD and its Characterization using XPS, TEM, and SE, Dhruv Shah

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Structures and Characteristics of Macromolecular Interactions in Gas Phase Using Fourier-Transform Ion Cyclotron Resonance Mass Spectrometry, Jiewen Shen

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The Role of the Chaperone CCT in Assembling Cell Signaling Complexes, Nicole C. Tensmeyer

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Capillary Morphogenesis Gene Protein 2 (CMG2) Mediates Matrix Protein Uptake and is Required for Endothelial Cell Chemotaxis in Response to Multiple Vascular Growth Factors, Tsz Ming Jeremy Tsang

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Design, Synthesis, and Characterization of New Non-Centrosymmetric Organic Crystals for Terahertz Generation, Gabriel Alejandro Valdivia-Berroeta

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Novel αvβ6 Inhibitor Reduces Fibrotic Progression in Idiopathic Pulmonary Fibrosis Murine Model, Rebecca C. Viazzo Winegar

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The Investigation of Functionalized Carbon Nanotubes for the Carbon Dioxide Capture and Ethane Oxidative Dehyrogenation Catalysts, Zheng Zhou

Theses/Dissertations from 2019

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3D Printed Microfluidic Devices for Bioanalysis, Michael J. Beauchamp

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The Investigation of Secondary Particle Formation Initiated by Non-Prototypical Sources and the role of Amines in the Atmosphere, Emily Burrell

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Inclusion of Kinetic Proteomics in Multi-Omics Methods to Analyze Calorie Restriction Effects on Aging, Richard Hajime Carson

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Applications of Pattern Recognition Entropy (PRE) and Informatics to Data Analysis, Shiladitya Chatterjee

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Multi-Instrument Surface Characterization of Display Glass, Cody Vic Cushman

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DNA Capture via Magnetic Beads in a Microfluidic Platformfor Rapid Detection of Antibiotic Resistance Genes, David Hyrum Harris

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Preparation, Functionalization, and/or Characterization by X-ray Photoelectron Spectroscopy of Carbon Surfaces for Biosensors and Other Materials, Varun Jain

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Preparation and Detailed X-Ray Photoelectron Spectroscopy and Spectroscopic EllipsometryAnalysis of Ultrathin Protective Coatings, Brian Ivins Johnson

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Computational Studies of High-Oxidation State Main-Group Metal Hydrocarbon C-H Functionalization, Clinton R. King

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Bifunctional Helical Peptide Catalysts for Enzyme-like Reactivity and Selectivity and Selective Stapling of Natural Amino Acid Residues with Hydrophilic Squaric Acid Derivatives, Michael James Kinghorn

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Computational Design and Analysis of Molecular Ethylene Oligomerization Catalysts, Doo Hyun Kwon

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Design and Synthesis of Ceragenins–Cationic Steroid Antimicrobial Compounds, Structural Improvement and Synthesis of Cyclopentenone Prostaglandins and Modification and Synthesis of Derivatives of Ribityllumazines: Potential Antigens for Activation of MAIT Cells, Yubo Li

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Design and Synthesis of TLR2 and TLR6 Heterodimer Ligands, a Triply Functionalized α-GalCer Derivative for Identifying Proteins Involved in Glycolipid Trafficking, and the Disaccharide of Staphylococcus aureus CP8 Towards a Self-Adjuvanting Vaccine, Sara Mayeth Mata

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Antibacterial and Antifungal Activity of Ceragenins, Mimics of Endogenous Antimicrobial Peptides, Marjan Mohammadihashemi

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Selective Catalysis by Polymer-Supported Ruthenium NanoparticlesAND New Ligand Design for Cooperative and Bimetallic Catalysis, Seyed Hadi Nazari

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The Investigation of Nickel-Based Catalysts for the Oxidative Dehydrogenation of Ethane, Justin Lane Park

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Exploration of Sputtered Thin Films—E.g., in Sample Preparation and Material Characterization, Tuhin Roychowdhury

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Total Synthesis of Anticancer Agent Deoxypodophyllotoxin and Antiviral F4-4 Demonstrating the Utility of the Intramolecular Styryl Diels-Alder (ISDA) Reaction, Diana Isabel Saavedra Nova

Theses/Dissertations from 2018

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An Introductory Study of Solid Materials for Capture and Catalysis of Waste Stream Chemicals, Steven Kyle Butler

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Endocytosis as an Additional Mechanism of Glucose Transport to the Hexose Transporter in Trypanosoma brucei, JongSu Choi

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Fluorescent Labeling of Antibiotic Resistant Bacteria Model DNA, Janice Darko

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The Use Of Tissue And Serum ”˜Omics' Methods To Characterize Disease, Ying Ding

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Contribution of Bulky <&alpha>,<&beta>-Dehydroamino Acids to the Proteolytic Stability andEnhanced Folding of <&beta>-Hairpins and Progress Towards the Total Synthesis of Yaku<'>amide A, Ankur Jalan

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Creation and Use of Software for Analysis of Kinetic Proteomic Experiments, Bradley C. Naylor

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Development of Affinity Monoliths in 3D Printed Microfluidic Devices for Extraction of Preterm Birth Biomarkers, Ellen Kelsey Parker

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Application of the Entropy Concept to Thermodynamics and Life Sciences: Evolution Parallels Thermodynamics, Cellulose Hydrolysis Thermodynamics, and Ordered and Disordered Vacancies Thermodynamics, Marko Popovic

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Measuring the Interaction and Cooperativity Between Ionic, Aromatic, and Nonpolar Amino Acids in Protein Structure, Mason Scott Smith

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Development and Use of Lipidomics and Proteomics Methods to Identify and Measure Pro-Survival Metabolic Pathways in Cancer, Monique Merilyn Speirs

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Synthesis and Determination of the Local Structure and Phase Evolution of Unique Boehmite-Derived Mesoporous Doped Aluminas, Ying Zhang

Theses/Dissertations from 2017

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Advancements in the Understanding of Nonlinear Optics and Their Use in Material Analysis, Shawn C. Averett

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Post-Translational Regulation of Superoxide Dismutase 1 (SOD1): The Effect of K122 Acylation on SOD1's Metabolic Activity, Courtney Jean Banks

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Microwave-Promoted Iminyl Radical Cyclizations for the Synthesis of Azaheterocycles and the Total Synthesis of Yaku'amide A, Yu Cai

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Role of Molecular Chaperonin CCT and Its Co-Chaperone PhLP1 in the Assembly of mTOR Complexes, Madhura Vinayak Dhavale

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Fundamental Studies and Applications of Ambient Plasma Ionization Sources for Mass Spectrometry, Wade C. Ellis

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Anthrax, Matrix Biology, and Angiogenesis: Capillary Morphogenesis Gene 2 Mediates Activity and Uptake of Type IV Collagen-Derived Anti-Angiogenic Peptides, Jordan Grant Finnell

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Ion Trajectory Simulations and Design Optimization of Toroidal Ion Trap Mass Spectrometers, Jessica Marie Higgs

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Microwave-Promoted Iminyl Radical Fragmentations: A Practical and Efficient Method of Functionalization, Mary Megan Jackman

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Ion Transport in a Commercial ICP-MS, Jessica Joline Larsen

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Desorption Electrospray Ionization (DESI) Mass Spectrometric Imaging of Spatially Regulated In Vivo Metabolic Rates, Charlotte Reininger Lewis

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Miniaturization of Linear Ion Traps and Ion Motion Study in a Toroidal Ion Trap Mass Analyzer, Ailin Li

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Capacity of Human Immunodeficiency Virus Targeting Chimeric Antigen Receptor T Cells to Eliminate Follicular Dendritic Cells Bearing Human Immunodeficiency Virus Immune Complexes, Matthew T. Ollerton

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Capacity of Human Immunodeficiency Virus Targeting Chimeric Antigen Receptor T Cells to Eliminate Follicular Dendritic Cells Bearing Human Immunodeficiency Virus Immune Complexes, Matthew T. Ollerton

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Acylation of Superoxide Dismutase 1 (SOD1) at K122 Alters SOD1 Localization and SOD1-Mediated Inhibition of Mitochondrial Respiration, Nathan William Rodriguez

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Semiconductor Terahertz Electronics and Novel High-Speed Single-Shot Measurements, Parker Dean Salmans

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Electrokinetically Operated Integrated Microfluidic Devices for Preterm Birth Biomarker Analysis, Mukul Sonker

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Ion Trap Miniaturization Considerations: Space-Charge Effects in Cylindrical Ion Traps and Misalignment Effects in a Two-Plate Linear Ion Trap, Yuan Tian

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Electrophilic Catalysis Using Heterobimetallic Complexes, Whitney Kaye Walker

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Functional and Mechanistic Insight into the Role of ATG9A in Autophagy, Vajira Kaushalya Weerasekara