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Keywords
Genetics, DNA, Histones, Epigenetics
Abstract
The structural organization of DNA in eukaryotic cells is greatly implicated in the regulation of gene expression and thus cellular properties and behavior. At the most fundamental unit of this organization, ~147 bp of DNA wraps 1.7 times around a histone octamer core, forming a collective unit called the nucleosome. The positioning and occupancy of these nucleosomes around the promoter elements of genes is known to be a strong regulator of transcription in eukaryotic nuclei, and post-translational modifications (PTM’s) to the protruding N-terminal tails of histone proteins are known to influence chromatin structure and thus gene expression; however, relatively little is known about the residual effect of histone PTM’s on transcription rate.
BYU ScholarsArchive Citation
Bohn, Aaron; Hodson, Sarah; Ricks, Sarah; Bates, David Ph.D; and Johnson, Steven M. Ph.D, "Effects of Post-Translational Histone Modifications on Transcription Rate" (2023). Library/Life Sciences Undergraduate Poster Competition 2023. 49.
https://scholarsarchive.byu.edu/library_studentposters_2023/49
Document Type
Poster
Publication Date
2023-02-23
Language
English
College
Life Sciences
Department
Microbiology and Molecular Biology
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