Assessing clinical trial eligibility with logic expression queries

Authors

Deryle W. Lonsdale, Brigham Young UniversityFollow
C. Tutison, Brigham Young UniversityFollow
Craig G. Parker, Brigham Young UniversityFollow
David W. Embley, Brigham Young UniversityFollow

Keywords

clinical trials, predicate logic, clinical data, virtual medical record

Abstract

This paper introduces a system that processes clinical trials using a combination of natural language processing and database techniques. We process web-based clinical trial recruitment pages to extract semantic information reflecting eligibility criteria for potential participants. From this information we then formulate a query that can match criteria against medical data in patient records. The resulting system reflects a tight coupling of web-based information extraction, natural language processing, medical informatic approaches to clinical knowledge representation, and large-scale database technologies. We present an evaluation of the system and future directions for further system development.

Original Publication Citation

D.W. Lonsdale, C. Tustison, C.G. Parker, D.W. Embley (2008). Assessing clinical trial eligibilitywith logic formula queries; Data and Knowledge Engineering 66(1), pp. 3-17. Elsevier B.V.ISSN 0169-023X.

BYU ScholarsArchive Citation

Lonsdale, Deryle W.; Tutison, C.; Parker, Craig G.; and Embley, David W., "Assessing clinical trial eligibility with logic expression queries" (2008). Faculty Publications. 6879.
https://scholarsarchive.byu.edu/facpub/6879

Document Type

Peer-Reviewed Article

Publication Date

2008

Publisher

Elsevier Ltd

Language

English

College

Humanities

Department

Linguistics

University Standing at Time of Publication

Associate Professor

Copyright Use Information

https://lib.byu.edu/about/copyright/