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Theses/Dissertations from 2024

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Using RNA Sequencing Methodologies to Uncover Common Pathways in Neural Tube Defects: A Comparative Study of Three Oxidative Neurotoxicants, Aubrey Coleen Johansen

Theses/Dissertations from 2022

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The Influence of THC, Opioids, and Age on the Plasticity of Excitatory Inputs to Ventral Tegmental Area GABA Neurons, Isaac Brent Ostlund

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Osteoarthritis and Cartilage Insult: Elucidation of Molecular Interplay and Attempted Interventions, Brandon James Rose

Theses/Dissertations from 2021

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Shaking Up the Immunoglobulin Superfamily, Christopher Mendoza

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Inflammation and Altered Signaling in Obstetric Pathologies, Ya-Fang Tsai

Theses/Dissertations from 2020

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RAGE and Gas6/Axl Signaling in Obstetric Complications, Kelsey May Hirschi Budge

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Valproic Acid Leads to an Increase in ROS Generation by Inhibiting the Deacetylation of Mitochondrial SOD, Stephen Marc Lucas

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Governing Dynamics of Divalent Copper Binding by Influenza A Matrix Protein 2 His37 Imidazole, Kelly Lewis McGuire

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A Comprehensive Comparison of Teratogenic Compounds Known to Induce Neural Tube Defects in the Chicken Embryo, Micah Marie Ross

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The Role of Beta-Hydroxybutyrate in Altering Adipose Mitochondrial Bioenergetics, Chase Mitchell Walton

Theses/Dissertations from 2019

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The Role of Growth Arrest Specific 6 and Axl Signaling in Skeletal Muscle Regeneration, Marc Shigeru Matsumura

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Role of Transient Receptor Potential Channels in Epithelial Morphogenesis in Chick Embryo, Trinity Q. Waddell

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A CRISPR/Cas9 Tissue Specific Forward Genetic Screening Method in Danio rerio, Joshua Don Yates

Theses/Dissertations from 2018

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Multi-Tissue Examination of Exercise or Metformin on the Consequences of Doxorubicin Treatment, Amy Dee MacKay

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CRISPR-Cas9 Transfection Optimization and Use in a Forward Genetic Screen to Identify Telomere Length Maintenance Genes, Kelsey Phillips

Theses/Dissertations from 2017

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MRI T2 Signal Changes Indicate Tau Pathophysiology in a Murine Alzheimer's Disease Model, Rajan Deep Adhikari

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Insulin and Ketones: Their Roles in Brain Mitochondrial Function, Sheryl Teresa Carr

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Insulin and Ketones: Their Roles in Brain Mitochondrial Function, Sheryl Teresa Carr

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LKB1 Regulation of High-Fat Diet-induced Adaptation in Mouse Skeletal Muscle, Ting Chen

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Modulation of Synaptic Plasticity: Endocannabinoids and Novel G-protein Coupled Receptors Expression and Translational Effects in Interneurons, Katrina M. Hurst

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Characterization of Neuronal Nicotinic Acetylcholine Receptors and their Positive Allosteric Modulators, Doris Clark Jackson

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Alterations in Tight Junctional Proteins and Their Effects on Pulmonary Inflammation, Joshua B. Lewis

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Pharmaceutical and Natural (Exercise) Mechanisms to Mitigate the Negative Impact of PTSD and Chronic Stress on Synaptic Plasticity and Memory, Roxanne M. Miller

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Pharmaceutical and Natural (Exercise) Mechanisms to Mitigate the Negative Impact of PTSD and Chronic Stress on Synaptic Plasticity and Memory, Roxanne M. Miller

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Chemogenetic Stimulation of Electrically Coupled Midbrain GABA Neurons in Alcohol Reward and Dependence, Stephanie Suzette Pistorius

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Chemogenetic Stimulation of Electrically Coupled Midbrain GABA Neurons in Alcohol Reward and Dependence, Stephanie Suzette Pistorius

Theses/Dissertations from 2016

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Identification and Characterization of Serum Biomarkers Associated with Breast Cancer Progression, Adhari Abdullah Alzaabi

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An Evaluation of the Influences of Extra-Hippocampal Processes on Pattern Separation, Malia L. Anderson

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The Effects of L-Cysteine on Alzheimer's Disease Pathology in APOE2, APOE3, and APOE4 Homozygous Mice, Stephen Gerard Cieslak

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A Neuroimaging Investigation of the Effects of Age and Sleep on Pattern Separation, Christopher Robert Doxey

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Endocannabinoid-Mediated Synaptic Plasticity in the Ventral Tegmental Area and Hippocampus, Lindsey Nicole Friend

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Rab8 Mediates TRPV4 Vesicle Trafficking to the Plasma Membrane in HGF-Stimulated MDCK Cells, Hillary Jean Haws

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Insulin Treatment Increases Myocardial Ceramide Accumulation and Disrupts Cardiometabolic Function, Aimee Elizabeth Hodson

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The Role of Hypoxia on Pyruvate Kinase M2, mammalian Target of Rapamycin, Mitochondrial Function, and Cell Invasion in the Trophoblast, Rebecca Lutz Kimball

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A Semi-Automated Algorithm for Segmenting the Hippocampus in Patient and Control Populations, Nathan McKay Muncy

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Glutamate and GABA Receptor-Mediated Plasticity in the Mesolimbic Dopamine System by Alcohol, Ashley Cerise Nelson

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Forward Chemical Genetics Drug Screen Yields Novel Proteases and Proteolytic Inhibitors of HGF–induced Epithelial–Mesenchymal Transition, Jeffrey Thomas Schuler

Theses/Dissertations from 2015

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Differential Receptors for Advanced Glycation End-Products (RAGE) Expression in Preeclampsia, Intrauterine Growth Restriction and Gestational Diabetes, Kristen Lena Alexander

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Third Ventricle Width as a Metric for Fast and Efficient Detection of Atrophy in Traumatic Brain Injury, Christopher Scott Finuf

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The Effects of Inhibiting Wnt Secretion and Activity on Cranial And Neural Development, Julie Louise Hulet

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The Biology of Claudin 6 (Cldn6) in the Developing Mouse Lung, Felix Ruben Jimenez Rondan

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The Anatomy of Porcine and Human Larynges: Structural Analysis and High Resolution Magnetic Resonance Imaging of the Recurrent Laryngeal Nerve, Nena Lundgreen Mason

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Calcium Signaling and Ca2+/Calmodulin-Dependent Kinase II Activity in Epithelial To Mesenchymal Transition, Melissa Ann McNeil

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The Role of Receptors for Advanced Glycation End-Products (RAGE) and Ceramide in Cardiovascular Disease, Michael Bruce Nelson

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HMGB1 and Ceramides: Potential Mediators of Cigarette Smoke-induced Metabolic Dysfunction, Mikayla Orton Thatcher

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Cigarette Smoke Increases Cardiomyocyte Ceramide Accumulation and Inhibits Mitochondrial Respiration, Trevor Stanley Tippetts

Theses/Dissertations from 2014

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Different Expression of Placental Pyruvate Kinase M2 in Normal, Preeclamptic, and Intrauterine Growth Restriction Pregnancies, Brigham L. Bahr

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Inhibition of PIM and AXL Kinases As Potential Treatments for a Variety of Hematological Malignancies and Solid Tumors, Kent James Carpenter

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Expression of Osteoarthritis Biomarkers in Temporomandibular Joints of Mice with and Without Receptor for Advanced Glycation End Products (RAGE), Elizabeth Murayama Chavez Matias

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Extent of Cysteine Modification of SNAP-25 In vitro, Alex McGregor DaBell

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Rapid Adaptation of Dopamine D2 Receptor Responses in the Brain and Blood Following Acute Ethanol, Ryan J. Folsom

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Divalent Copper Compounds as Inhibitory Agents of Influenza A, Nathan Allan Gordon

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The Role of Ceramides in Mediating Endotoxin-Induced Mitochondrial Disruption, Melissa Ellen Hansen

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The Effects of Aging on Skeletal Muscle AMPK Activation and an Analysis of Chronic AICAR Treatment on the Aging Phenotype, Shalene E. Hardman

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Synaptic Plasticity in GABAergic Inhibition of VTA Neurons, Jennifer Kei Mabey

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Endocannabinoid Biosynthetic Enzyme mRNA: Patterns of Expression in Hippocampus and Ventral Tegmental Area and Effects on Synaptic Plasticity, Collin Brutch Merrill

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Examination of Anabolic Signaling and Muscle Growth with Caffeine Treatment in Overloaded Hindlimb Muscle and Electrically Stimulated Muscle Lacking Liver Kinase B1, Timothy Michael Moore

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Alcohol Modulation of Dopamine Release, Nathan Dan Schilaty

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Role of α6 nAChRs in Ethanol Modulation of VTA Neurons, Samuel Injae Shin

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Characterization of Secondhand Smoke (SHS) and Materno-Fetal Interactions in Receptors for Advanced Glycation End-Products (RAGE)-Targeted Mice, Duane Ray Winden

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Targeting of Receptors for Advanced Glycation End-Products (RAGE) Diminishes Acute Secondhand Smoke-Induced Inflammation in Mice, Tyler Thomas Wood

Theses/Dissertations from 2013

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FGF4 Induced Wnt5a Gradient in the Limb Bud Mediates Mesenchymal Cell Directed Migration and Division, John C. Allen

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Involvement of AMPK and AP-1 Biochemical Pathways in IL-6 Regulation of Steroidogenic Enzymes in the Adrenal Cortex, Matharage Shenali De Silva

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Susceptibility of Apoptotic Cells to Hydrolysis by sPLA2: Molecular Basis and Mechanisms Defined, Elizabeth Gibbons

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Beta-Amyloid Inhibition of Alpha 7 Nicotinic Acetylcholine Receptors and Factors That Potentially Influence the Aβ/nAChR Interaction, Christopher L. Jacobsen

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A Model for Sensory Neuron Development by FGF and Notch: A Multifactorial Approach, Jacob Eugene Voelkel

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Endocannabinoid-Dependent Long-Term Depression of Ventral Tegmental Area GABA Neurons, Jared Mark Weed

Theses/Dissertations from 2012

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Regulation of Sensory Neurogenesis in the Trigeminal Placode: Notch Pathway Genes, Pax3 Isoforms, and Wnt Ligands, Jason Samuel Adams

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Membrane Properties Involved in Calcium-Stimulated Microparticle Release from the Plasma Membranes of S49 Lymphoma Cells, Lauryl Elizabeth Campbell

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Iron Deficiency Causes a Shift in AMP-Activated Protein Kinase (AMPK) Catalytic Subunit Composition in Rat Skeletal Muscle, John Merrill

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The Pro-Inflammatory Contributions of Receptors for Advanced Glycation End-Products (RAGE) in Alveolar Macrophages Following Cigarette Smoke Exposure, Adam Benjamin Robinson

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Long-Term Depression of Excitatory Inputs to GABAergic Neurons in the Ventral Tegmental Area, Philip J. Sandoval

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Tissue Specific Porcupine Deletion Reveals a Novel Role for Ectodermal Wnts in Musculotendon Development, Aaron P. Smith

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Characterization of Altered Epithelial Cell Turnover and Differentiation in Embryonic Murine Lungs That Over-Express Receptors for Advanced Glycation End-Products (RAGE), Jeffrey Alan Stogsdill

Theses/Dissertations from 2011

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The Effects of β-Amyloid on α7 Nicotinic Acetylcholine Receptors Expressed in Xenopus Oocytes, Malia L. Anderson

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Role of Wnt5a and Possible Pathway of Action Through Ror2 in Proximodistal Outgrowth of the Limb, Tiffanie M. Dahl

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Possible Molecular Mechanism to Account for Wavelength Dependence of Equilibration Rates of Patman and Laurdan in Phosphatidylcholine Bilayers, Hannabeth A. Franchino

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Calcineurin is Required for TRPV1-induced LTD of CA1 Stratum Radiatum Interneurons, Tyron DeRay Jensen

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Mechanisms of Prenatal High-Salt "Fetal Programming" Resulting in Stress Hyperresponsiveness in The Adult Female Offspring in The Sprague Dawley Rat., Clinton L. Johnson

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c-Met Initiates Epithelial Scattering through Transient Calcium Influxes and NFAT-Dependent Gene Transcription, Peter R. Langford

Theses/Dissertations from 2010

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Anti-Depressive and Anti-Obesity Changes Following Either Dietary Isoflavone Treatment or Injection Treatment with the Isoflavonoid Equol: Positive Response Dependent on Animal Age and Ovarian Status in Female Long Evans Rats, Crystal Blake

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Liver Kinase B1/AMP-Activated Protein Kinase Signaling in the Diaphragm, Jacob D. Brown

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Role of AMPK in the Upregulation of Steroidogenic Acute Regulatory Protein in the Zona Fasciculata of the Adrenal Cortex, Adam Wesley Dayton

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Chronic AMP-Activated Protein Kinase Activation and a High-Fat Diet Have an Additive Effect on Mitochondria in Rat Skeletal Muscle, Natasha Fillmore

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Proteoliposome Proton Flux Assays Establish Net Conductance, pH-Sensitivity, and Functional Integrity of a Novel Truncate of the M2 Ion "Channel" of Influenza A, Emily Peterson

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Characterization of the LKB1-MO25-STRAD AMPKK Complex in Adult Mouse Skeletal Muscle, Cody Don Smith

Theses/Dissertations from 2009

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Function of the Notch/Delta Pathway in Ophthalmic Trigeminal Placode Development, Matthew K. Ball

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Molecular and Cellular Mechanisms Whereby the Apical Ectodermal Ridge (AER), Via Wnt5a, Mediates Directional Migration of the Adjacent Mesenchyme During Vertebrate Limb Development, Kate E. Kmetzsch

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Zyxin Regulates Epithelial-Mesenchymal Transition by Mediating Actin-Membrane Linkages at Cell-Cell Junctions, Liv Rebecca Sperry

Theses/Dissertations from 2008

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Mechanisms by Which Apoptotic Membranes Become Susceptible to Secretory Phospholipase A2, Rachel Williams Bailey

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Wnt5a Signaling Independently of the Planar Cell Polarity Pathway Resulting in Convergent Extension and Neural Tube Closure During Vertebrate Development, Jared James Barrott

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The Effects of Prenatally Administered Phytoestrogens on the Reproductive and Behavioral Development of Long-Evans Rats, Crystal Blake

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The Effects of a Resveratrol Derivative on Regulatory Behaviors and Reproductive Health in Male and Female Long-Evans Rats, Kimberly Michelle Fabick

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Differential Expression and Functional Characterization of Alpha3 Beta2 Neuronal Nicotinic Acetylcholine Receptors, John Hideo Mizukawa

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The Effects of Excess Corticosterone on LKB1 and AMPK Signaling in Skeletal Muscle of Rats, Gary N. Nakken

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Investigating and Modeling Possible Mechanisms by Which Healthy Cell Membranes Become Resistant to Hydrolysis by Secretory Phospholipase A2, Jennifer Nelson

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A Comparative Analysis of Hydrolysis Kinetics by sPLA2 Isoforms During Apoptosis in S49 Cells, Erin Dalene Olson

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Cellular and Matrix Changes in Articular Cartilage of the Disproportionate micromelia Mouse Model of Osteoarthritis, Crystal Noelle Smaldone

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Determining the Role of Wnt5a Signaling in Embryonic Limb Outgrowth via Clonal Analysis, Whitney Herrod Sowby

Theses/Dissertations from 2007

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Regulation of LKB1-STRAD-MO25 Complex Expression and Activation of AMPK in Skeletal Muscle by Thyroid Hormone, Devon Jack Branvold