Theses/Dissertations from 2024
Using RNA Sequencing Methodologies to Uncover Common Pathways in Neural Tube Defects: A Comparative Study of Three Oxidative Neurotoxicants, Aubrey Coleen Johansen
Theses/Dissertations from 2022
The Influence of THC, Opioids, and Age on the Plasticity of Excitatory Inputs to Ventral Tegmental Area GABA Neurons, Isaac Brent Ostlund
Osteoarthritis and Cartilage Insult: Elucidation of Molecular Interplay and Attempted Interventions, Brandon James Rose
Theses/Dissertations from 2021
Shaking Up the Immunoglobulin Superfamily, Christopher Mendoza
Inflammation and Altered Signaling in Obstetric Pathologies, Ya-Fang Tsai
Theses/Dissertations from 2020
RAGE and Gas6/Axl Signaling in Obstetric Complications, Kelsey May Hirschi Budge
Valproic Acid Leads to an Increase in ROS Generation by Inhibiting the Deacetylation of Mitochondrial SOD, Stephen Marc Lucas
Governing Dynamics of Divalent Copper Binding by Influenza A Matrix Protein 2 His37 Imidazole, Kelly Lewis McGuire
A Comprehensive Comparison of Teratogenic Compounds Known to Induce Neural Tube Defects in the Chicken Embryo, Micah Marie Ross
The Role of Beta-Hydroxybutyrate in Altering Adipose Mitochondrial Bioenergetics, Chase Mitchell Walton
Theses/Dissertations from 2019
The Role of Growth Arrest Specific 6 and Axl Signaling in Skeletal Muscle Regeneration, Marc Shigeru Matsumura
Role of Transient Receptor Potential Channels in Epithelial Morphogenesis in Chick Embryo, Trinity Q. Waddell
A CRISPR/Cas9 Tissue Specific Forward Genetic Screening Method in Danio rerio, Joshua Don Yates
Theses/Dissertations from 2018
Multi-Tissue Examination of Exercise or Metformin on the Consequences of Doxorubicin Treatment, Amy Dee MacKay
CRISPR-Cas9 Transfection Optimization and Use in a Forward Genetic Screen to Identify Telomere Length Maintenance Genes, Kelsey Phillips
Theses/Dissertations from 2017
MRI T2 Signal Changes Indicate Tau Pathophysiology in a Murine Alzheimer's Disease Model, Rajan Deep Adhikari
Insulin and Ketones: Their Roles in Brain Mitochondrial Function, Sheryl Teresa Carr
Insulin and Ketones: Their Roles in Brain Mitochondrial Function, Sheryl Teresa Carr
LKB1 Regulation of High-Fat Diet-induced Adaptation in Mouse Skeletal Muscle, Ting Chen
Modulation of Synaptic Plasticity: Endocannabinoids and Novel G-protein Coupled Receptors Expression and Translational Effects in Interneurons, Katrina M. Hurst
Characterization of Neuronal Nicotinic Acetylcholine Receptors and their Positive Allosteric Modulators, Doris Clark Jackson
Alterations in Tight Junctional Proteins and Their Effects on Pulmonary Inflammation, Joshua B. Lewis
Pharmaceutical and Natural (Exercise) Mechanisms to Mitigate the Negative Impact of PTSD and Chronic Stress on Synaptic Plasticity and Memory, Roxanne M. Miller
Pharmaceutical and Natural (Exercise) Mechanisms to Mitigate the Negative Impact of PTSD and Chronic Stress on Synaptic Plasticity and Memory, Roxanne M. Miller
Chemogenetic Stimulation of Electrically Coupled Midbrain GABA Neurons in Alcohol Reward and Dependence, Stephanie Suzette Pistorius
Chemogenetic Stimulation of Electrically Coupled Midbrain GABA Neurons in Alcohol Reward and Dependence, Stephanie Suzette Pistorius
Theses/Dissertations from 2016
Identification and Characterization of Serum Biomarkers Associated with Breast Cancer Progression, Adhari Abdullah Alzaabi
An Evaluation of the Influences of Extra-Hippocampal Processes on Pattern Separation, Malia L. Anderson
The Effects of L-Cysteine on Alzheimer's Disease Pathology in APOE2, APOE3, and APOE4 Homozygous Mice, Stephen Gerard Cieslak
A Neuroimaging Investigation of the Effects of Age and Sleep on Pattern Separation, Christopher Robert Doxey
Endocannabinoid-Mediated Synaptic Plasticity in the Ventral Tegmental Area and Hippocampus, Lindsey Nicole Friend
Rab8 Mediates TRPV4 Vesicle Trafficking to the Plasma Membrane in HGF-Stimulated MDCK Cells, Hillary Jean Haws
Insulin Treatment Increases Myocardial Ceramide Accumulation and Disrupts Cardiometabolic Function, Aimee Elizabeth Hodson
The Role of Hypoxia on Pyruvate Kinase M2, mammalian Target of Rapamycin, Mitochondrial Function, and Cell Invasion in the Trophoblast, Rebecca Lutz Kimball
A Semi-Automated Algorithm for Segmenting the Hippocampus in Patient and Control Populations, Nathan McKay Muncy
Glutamate and GABA Receptor-Mediated Plasticity in the Mesolimbic Dopamine System by Alcohol, Ashley Cerise Nelson
Forward Chemical Genetics Drug Screen Yields Novel Proteases and Proteolytic Inhibitors of HGF–induced Epithelial–Mesenchymal Transition, Jeffrey Thomas Schuler
Theses/Dissertations from 2015
Differential Receptors for Advanced Glycation End-Products (RAGE) Expression in Preeclampsia, Intrauterine Growth Restriction and Gestational Diabetes, Kristen Lena Alexander
Third Ventricle Width as a Metric for Fast and Efficient Detection of Atrophy in Traumatic Brain Injury, Christopher Scott Finuf
The Effects of Inhibiting Wnt Secretion and Activity on Cranial And Neural Development, Julie Louise Hulet
The Biology of Claudin 6 (Cldn6) in the Developing Mouse Lung, Felix Ruben Jimenez Rondan
The Anatomy of Porcine and Human Larynges: Structural Analysis and High Resolution Magnetic Resonance Imaging of the Recurrent Laryngeal Nerve, Nena Lundgreen Mason
Calcium Signaling and Ca2+/Calmodulin-Dependent Kinase II Activity in Epithelial To Mesenchymal Transition, Melissa Ann McNeil
The Role of Receptors for Advanced Glycation End-Products (RAGE) and Ceramide in Cardiovascular Disease, Michael Bruce Nelson
HMGB1 and Ceramides: Potential Mediators of Cigarette Smoke-induced Metabolic Dysfunction, Mikayla Orton Thatcher
Cigarette Smoke Increases Cardiomyocyte Ceramide Accumulation and Inhibits Mitochondrial Respiration, Trevor Stanley Tippetts
Theses/Dissertations from 2014
Different Expression of Placental Pyruvate Kinase M2 in Normal, Preeclamptic, and Intrauterine Growth Restriction Pregnancies, Brigham L. Bahr
Inhibition of PIM and AXL Kinases As Potential Treatments for a Variety of Hematological Malignancies and Solid Tumors, Kent James Carpenter
Expression of Osteoarthritis Biomarkers in Temporomandibular Joints of Mice with and Without Receptor for Advanced Glycation End Products (RAGE), Elizabeth Murayama Chavez Matias
Extent of Cysteine Modification of SNAP-25 In vitro, Alex McGregor DaBell
Rapid Adaptation of Dopamine D2 Receptor Responses in the Brain and Blood Following Acute Ethanol, Ryan J. Folsom
Divalent Copper Compounds as Inhibitory Agents of Influenza A, Nathan Allan Gordon
The Role of Ceramides in Mediating Endotoxin-Induced Mitochondrial Disruption, Melissa Ellen Hansen
The Effects of Aging on Skeletal Muscle AMPK Activation and an Analysis of Chronic AICAR Treatment on the Aging Phenotype, Shalene E. Hardman
Synaptic Plasticity in GABAergic Inhibition of VTA Neurons, Jennifer Kei Mabey
Endocannabinoid Biosynthetic Enzyme mRNA: Patterns of Expression in Hippocampus and Ventral Tegmental Area and Effects on Synaptic Plasticity, Collin Brutch Merrill
Examination of Anabolic Signaling and Muscle Growth with Caffeine Treatment in Overloaded Hindlimb Muscle and Electrically Stimulated Muscle Lacking Liver Kinase B1, Timothy Michael Moore
Alcohol Modulation of Dopamine Release, Nathan Dan Schilaty
Role of α6 nAChRs in Ethanol Modulation of VTA Neurons, Samuel Injae Shin
Characterization of Secondhand Smoke (SHS) and Materno-Fetal Interactions in Receptors for Advanced Glycation End-Products (RAGE)-Targeted Mice, Duane Ray Winden
Targeting of Receptors for Advanced Glycation End-Products (RAGE) Diminishes Acute Secondhand Smoke-Induced Inflammation in Mice, Tyler Thomas Wood
Theses/Dissertations from 2013
FGF4 Induced Wnt5a Gradient in the Limb Bud Mediates Mesenchymal Cell Directed Migration and Division, John C. Allen
Involvement of AMPK and AP-1 Biochemical Pathways in IL-6 Regulation of Steroidogenic Enzymes in the Adrenal Cortex, Matharage Shenali De Silva
Susceptibility of Apoptotic Cells to Hydrolysis by sPLA2: Molecular Basis and Mechanisms Defined, Elizabeth Gibbons
Beta-Amyloid Inhibition of Alpha 7 Nicotinic Acetylcholine Receptors and Factors That Potentially Influence the Aβ/nAChR Interaction, Christopher L. Jacobsen
A Model for Sensory Neuron Development by FGF and Notch: A Multifactorial Approach, Jacob Eugene Voelkel
Endocannabinoid-Dependent Long-Term Depression of Ventral Tegmental Area GABA Neurons, Jared Mark Weed
Theses/Dissertations from 2012
Regulation of Sensory Neurogenesis in the Trigeminal Placode: Notch Pathway Genes, Pax3 Isoforms, and Wnt Ligands, Jason Samuel Adams
Membrane Properties Involved in Calcium-Stimulated Microparticle Release from the Plasma Membranes of S49 Lymphoma Cells, Lauryl Elizabeth Campbell
Iron Deficiency Causes a Shift in AMP-Activated Protein Kinase (AMPK) Catalytic Subunit Composition in Rat Skeletal Muscle, John Merrill
The Pro-Inflammatory Contributions of Receptors for Advanced Glycation End-Products (RAGE) in Alveolar Macrophages Following Cigarette Smoke Exposure, Adam Benjamin Robinson
Long-Term Depression of Excitatory Inputs to GABAergic Neurons in the Ventral Tegmental Area, Philip J. Sandoval
Tissue Specific Porcupine Deletion Reveals a Novel Role for Ectodermal Wnts in Musculotendon Development, Aaron P. Smith
Characterization of Altered Epithelial Cell Turnover and Differentiation in Embryonic Murine Lungs That Over-Express Receptors for Advanced Glycation End-Products (RAGE), Jeffrey Alan Stogsdill
Theses/Dissertations from 2011
The Effects of β-Amyloid on α7 Nicotinic Acetylcholine Receptors Expressed in Xenopus Oocytes, Malia L. Anderson
Role of Wnt5a and Possible Pathway of Action Through Ror2 in Proximodistal Outgrowth of the Limb, Tiffanie M. Dahl
Possible Molecular Mechanism to Account for Wavelength Dependence of Equilibration Rates of Patman and Laurdan in Phosphatidylcholine Bilayers, Hannabeth A. Franchino
Calcineurin is Required for TRPV1-induced LTD of CA1 Stratum Radiatum Interneurons, Tyron DeRay Jensen
Mechanisms of Prenatal High-Salt "Fetal Programming" Resulting in Stress Hyperresponsiveness in The Adult Female Offspring in The Sprague Dawley Rat., Clinton L. Johnson
c-Met Initiates Epithelial Scattering through Transient Calcium Influxes and NFAT-Dependent Gene Transcription, Peter R. Langford
Theses/Dissertations from 2010
Liver Kinase B1/AMP-Activated Protein Kinase Signaling in the Diaphragm, Jacob D. Brown
Role of AMPK in the Upregulation of Steroidogenic Acute Regulatory Protein in the Zona Fasciculata of the Adrenal Cortex, Adam Wesley Dayton
Chronic AMP-Activated Protein Kinase Activation and a High-Fat Diet Have an Additive Effect on Mitochondria in Rat Skeletal Muscle, Natasha Fillmore
Characterization of the LKB1-MO25-STRAD AMPKK Complex in Adult Mouse Skeletal Muscle, Cody Don Smith
Theses/Dissertations from 2009
Function of the Notch/Delta Pathway in Ophthalmic Trigeminal Placode Development, Matthew K. Ball
Zyxin Regulates Epithelial-Mesenchymal Transition by Mediating Actin-Membrane Linkages at Cell-Cell Junctions, Liv Rebecca Sperry
Theses/Dissertations from 2008
Mechanisms by Which Apoptotic Membranes Become Susceptible to Secretory Phospholipase A2, Rachel Williams Bailey
Wnt5a Signaling Independently of the Planar Cell Polarity Pathway Resulting in Convergent Extension and Neural Tube Closure During Vertebrate Development, Jared James Barrott
The Effects of Prenatally Administered Phytoestrogens on the Reproductive and Behavioral Development of Long-Evans Rats, Crystal Blake
The Effects of a Resveratrol Derivative on Regulatory Behaviors and Reproductive Health in Male and Female Long-Evans Rats, Kimberly Michelle Fabick
Differential Expression and Functional Characterization of Alpha3 Beta2 Neuronal Nicotinic Acetylcholine Receptors, John Hideo Mizukawa
The Effects of Excess Corticosterone on LKB1 and AMPK Signaling in Skeletal Muscle of Rats, Gary N. Nakken
Investigating and Modeling Possible Mechanisms by Which Healthy Cell Membranes Become Resistant to Hydrolysis by Secretory Phospholipase A2, Jennifer Nelson
A Comparative Analysis of Hydrolysis Kinetics by sPLA2 Isoforms During Apoptosis in S49 Cells, Erin Dalene Olson
Cellular and Matrix Changes in Articular Cartilage of the Disproportionate micromelia Mouse Model of Osteoarthritis, Crystal Noelle Smaldone
Determining the Role of Wnt5a Signaling in Embryonic Limb Outgrowth via Clonal Analysis, Whitney Herrod Sowby
Theses/Dissertations from 2007
Regulation of LKB1-STRAD-MO25 Complex Expression and Activation of AMPK in Skeletal Muscle by Thyroid Hormone, Devon Jack Branvold