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Keywords
migraine, metabolism, ketone, diet, therapy
Abstract
Honorable Mention - Open House Presentation
- Spreading depolarization (SD) is a slow-moving wave of ionic redistribution.
- SDs propagate through cortical tissue in patients experiencing migraine with aura, as well as traumatic brain injury (TBI), ischemic stroke, and seizure.
- Recovery of ionic homeostasis following SD is metabolically taxing; an energetic deficit is associated with long-term mitochondrial damage.
- Ketone body supplementation is a promising therapeutic for epilepsy and migraine, although its mechanisms are not fully understood.
BYU ScholarsArchive Citation
Shafer, T. Luke; Nevers, Dallin S.; Ricks, Rachel; Dunford, Clayton; Poulos, Tyler; Stubbs, Isaac; Cheney, Coleson; Bikman, Benjamin T.; and Parrish, R. Ryley, "Ketone Bodies May Mitigate Metabolic Dysfunction in a Model of Migraine" (2026). Library/Life Sciences Undergraduate Poster Competition 2026. 21.
https://scholarsarchive.byu.edu/library_studentposters_2026/21
Document Type
Poster
Publication Date
2026-03-26
Language
English
College
Life Sciences
Department
Neuroscience
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