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Developmental defects, tight junctions, Junctional adhesion molecule (JAM)
Development of the central nervous system, the brain and the spinal cord, starts initially with the formation of the neural tube. This vital process starts as a sheet of cells which then folds into a cylindrical structure in the early stages of embryo development (Fig1). Defects in the formation of the neural tube can lead to permanent disabilities in babies after birth. This is important to understand as current statistics show that approximately 300,000 babies are born annually with neural tube defects. (NTDs). In addition to NTDs there are many other dangerous birth defects that are important to understand as we work towards prevention and treatment.
BYU ScholarsArchive Citation
Allen, Wesley; Beckett, Nathan; Hall, Lauren; Holdaway, Emma; Jung, Sion; Mann, Meredith; Thacker, Spencer; Wengler, Jacob; Winn, Cailey; Mizrachi, Dario; and Stark, Michael, "Interruption of Junctional Adhesion Molecules Shows Developmental Defects" (2022). Library/Life Sciences Undergraduate Poster Competition 2022. 40.
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