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Keywords

Developmental defects, tight junctions, Junctional adhesion molecule (JAM)

Abstract

Development of the central nervous system, the brain and the spinal cord, starts initially with the formation of the neural tube. This vital process starts as a sheet of cells which then folds into a cylindrical structure in the early stages of embryo development (Fig1). Defects in the formation of the neural tube can lead to permanent disabilities in babies after birth. This is important to understand as current statistics show that approximately 300,000 babies are born annually with neural tube defects. (NTDs). In addition to NTDs there are many other dangerous birth defects that are important to understand as we work towards prevention and treatment.

Document Type

Poster

Publication Date

2022-3

Language

English

College

Life Sciences

Department

Exercise Sciences

University Standing at Time of Publication

Senior

Interruption of Junctional Adhesion Molecules Shows Developmental Defects

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