A Single-Cell Bioinformatics Analysis of the Host Transcriptional Response to Infection Consisting of Natural Combinations of Influenza A Virus Gene Segments
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Influenza A, gene segments, host transcriptional response
Influenza A viruses (IAV) have a segmented, negative-sense RNA genome (complementary to RNA transcript) that is composed of eight segments, which code for the structural and nonstructural genes needed for viral infection and replication. Although each of these segments play a specific role, past experiments have shown that not all segments are expressed within infected cells, requiring multiple viruses to enter a cell to produce a productive infection.
BYU ScholarsArchive Citation
Howell, Jacquelyne; Jackson, Caroline; Scott, Tiana M.; Lowen, Anice C.; Tan, Gene S.; and Pickett, Brett E., "A Single-Cell Bioinformatics Analysis of the Host Transcriptional Response to Infection Consisting of Natural Combinations of Influenza A Virus Gene Segments" (2021). Library/Life Sciences Undergraduate Poster Competition 2021. 34.
Physiology and Developmental Biology
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