BYU ScholarsArchive

Title

A Single-Cell Bioinformatics Analysis of the Host Transcriptional Response to Infection Consisting of Natural Combinations of Influenza A Virus Gene Segments

Authors

Jacquelyne Howell, Brigham Young University - ProvoFollow
Caroline Jackson, Brigham Young University - Provo
Tiana M. Scott, Brigham Young University - Provo
Anice C. Lowen, Emory University
Gene S. Tan, University of California San Diego
Brett E. Pickett, Brigham Young University - ProvoFollow

Files

Keywords

Influenza A, gene segments, host transcriptional response

Abstract

Influenza A viruses (IAV) have a segmented, negative-sense RNA genome (complementary to RNA transcript) that is composed of eight segments, which code for the structural and nonstructural genes needed for viral infection and replication. Although each of these segments play a specific role, past experiments have shown that not all segments are expressed within infected cells, requiring multiple viruses to enter a cell to produce a productive infection.

BYU ScholarsArchive Citation

Howell, Jacquelyne; Jackson, Caroline; Scott, Tiana M.; Lowen, Anice C.; Tan, Gene S.; and Pickett, Brett E., "A Single-Cell Bioinformatics Analysis of the Host Transcriptional Response to Infection Consisting of Natural Combinations of Influenza A Virus Gene Segments" (2021). Library/Life Sciences Undergraduate Poster Competition 2021. 34.
https://scholarsarchive.byu.edu/library_studentposters_2021/34

Document Type

Video

Publication Date

2021

Language

English

College

Life Sciences

Department

Physiology and Developmental Biology

University Standing at Time of Publication

Sophomore

Copyright Use Information

http://lib.byu.edu/about/copyright/