Keywords
Non-suicidal self injury, Neurobiology, Neuroimaging, RDoC
Abstract
Non-suicidal self-injury (NSSI) commonly starts in adolescence and is associated with an array of negative outcomes. Neurobiological research investigating NSSI is in its early stages and most studies have examined this behavior within the context of specific diagnoses. However, the Research Domain Criteria (RDoC) initiative encourages researchers to examine brain-behavior relationships across diagnoses. This review on the neurobiology associated with NSSI is organized using the domains proposed by RDoC: Negative Valence, Positive Valence, Cognitive, Social Processes, and Arousal/Regulatory Systems. Evidence of neurobiological anomalies is found in each of these domains. We also propose future research directions, especially in regard to human development. Future NSSI studies should address this behavior independent of diagnosis, examine relevant constructs across multiple units of analysis, and assess how systems change across development and course of illness. These advances will be essential for guiding neurobiologically informed intervention and prevention strategies to target NSSI. In doing so, we may prevent the associated negative outcomes across the lifespan.
BYU ScholarsArchive Citation
Braithwaite, Scott R.; Westlund Schreiner, Melinda; Klimes-Dougan, Bonnie; Begnel, Erin D.; and Cullen, Kathryn R., "Conceptualizing the neurobiology of non-suicidal self-injury from the perspective of the Research Domain Criteria Project" (2017). Faculty Publications. 6002.
https://scholarsarchive.byu.edu/facpub/6002
Document Type
Peer-Reviewed Article
Publication Date
2017
Permanent URL
http://hdl.lib.byu.edu/1877/8731
Language
English
College
Family, Home, and Social Sciences
Department
Psychology