Keywords

phase transitions, gene delivery, ultrasound

Abstract

A computer model was written that simulates the transformation of a nanoemulsion droplet to a gas bubble by the application of ultrasound. Experimentally such a technique could be used to enhance non-viral gene transfection beyond the boundary of the endothelial lining of the circulatory system, particularly in tumors exhibiting enhanced permeation and retention of nanoparticles.

Original Publication Citation

Pitt, W.G., Singh, R., and Husseini, G.A. "Modeling Phase Transitions of Nanoemulsions for Ultrasonic Gene Delivery", Annual Meeting of the Controlled Release Society, 35, 692, New York, NY, July 13-16, 28

Document Type

Poster

Publication Date

2008-07-13

Permanent URL

http://hdl.lib.byu.edu/1877/2130

Language

English

College

Ira A. Fulton College of Engineering and Technology

Department

Chemical Engineering

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