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Theses/Dissertations from 2017

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Alterations in Tight Junctional Proteins and Their Effects on Pulmonary Inflammation, Joshua B. Lewis

Theses/Dissertations from 2016

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An Evaluation of the Influences of Extra-Hippocampal Processes on Pattern Separation, Malia L. Anderson

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A Neuroimaging Investigation of the Effects of Age and Sleep on Pattern Separation, Christopher Robert Doxey

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Rab8 Mediates TRPV4 Vesicle Trafficking to the Plasma Membrane in HGF-Stimulated MDCK Cells, Hillary Jean Haws

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Insulin Treatment Increases Myocardial Ceramide Accumulation and Disrupts Cardiometabolic Function, Aimee Elizabeth Hodson

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The Role of Hypoxia on Pyruvate Kinase M2, mammalian Target of Rapamycin, Mitochondrial Function, and Cell Invasion in the Trophoblast, Rebecca Lutz Kimball

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Forward Chemical Genetics Drug Screen Yields Novel Proteases and Proteolytic Inhibitors of HGF–induced Epithelial–Mesenchymal Transition, Jeffrey Thomas Schuler

Theses/Dissertations from 2015

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Differential Receptors for Advanced Glycation End-Products (RAGE) Expression in Preeclampsia, Intrauterine Growth Restriction and Gestational Diabetes, Kristen Lena Alexander

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Third Ventricle Width as a Metric for Fast and Efficient Detection of Atrophy in Traumatic Brain Injury, Christopher Scott Finuf

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The Effects of Inhibiting Wnt Secretion and Activity on Cranial And Neural Development, Julie Louise Hulet

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The Biology of Claudin 6 (Cldn6) in the Developing Mouse Lung, Felix Ruben Jimenez Rondan

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The Anatomy of Porcine and Human Larynges: Structural Analysis and High Resolution Magnetic Resonance Imaging of the Recurrent Laryngeal Nerve, Nena Lundgreen Mason

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Calcium Signaling and Ca2+/Calmodulin-Dependent Kinase II Activity in Epithelial To Mesenchymal Transition, Melissa Ann McNeil

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The Role of Receptors for Advanced Glycation End-Products (RAGE) and Ceramide in Cardiovascular Disease, Michael Bruce Nelson

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HMGB1 and Ceramides: Potential Mediators of Cigarette Smoke-induced Metabolic Dysfunction, Mikayla Orton Thatcher

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Cigarette Smoke Increases Cardiomyocyte Ceramide Accumulation and Inhibits Mitochondrial Respiration, Trevor Stanley Tippetts

Theses/Dissertations from 2014

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Different Expression of Placental Pyruvate Kinase M2 in Normal, Preeclamptic, and Intrauterine Growth Restriction Pregnancies, Brigham L. Bahr

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Inhibition of PIM and AXL Kinases As Potential Treatments for a Variety of Hematological Malignancies and Solid Tumors, Kent James Carpenter

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Expression of Osteoarthritis Biomarkers in Temporomandibular Joints of Mice with and Without Receptor for Advanced Glycation End Products (RAGE), Elizabeth Murayama Chavez Matias

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Extent of Cysteine Modification of SNAP-25 In vitro, Alex McGregor DaBell

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Rapid Adaptation of Dopamine D2 Receptor Responses in the Brain and Blood Following Acute Ethanol, Ryan J. Folsom

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Divalent Copper Compounds as Inhibitory Agents of Influenza A, Nathan Allan Gordon

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The Role of Ceramides in Mediating Endotoxin-Induced Mitochondrial Disruption, Melissa Ellen Hansen

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The Effects of Aging on Skeletal Muscle AMPK Activation and an Analysis of Chronic AICAR Treatment on the Aging Phenotype, Shalene E. Hardman

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Synaptic Plasticity in GABAergic Inhibition of VTA Neurons, Jennifer Kei Mabey

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Endocannabinoid Biosynthetic Enzyme mRNA: Patterns of Expression in Hippocampus and Ventral Tegmental Area and Effects on Synaptic Plasticity, Collin Brutch Merrill

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Examination of Anabolic Signaling and Muscle Growth with Caffeine Treatment in Overloaded Hindlimb Muscle and Electrically Stimulated Muscle Lacking Liver Kinase B1, Timothy Michael Moore

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Alcohol Modulation of Dopamine Release, Nathan Dan Schilaty

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Role of α6 nAChRs in Ethanol Modulation of VTA Neurons, Samuel Injae Shin

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Characterization of Secondhand Smoke (SHS) and Materno-Fetal Interactions in Receptors for Advanced Glycation End-Products (RAGE)-Targeted Mice, Duane Ray Winden

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Targeting of Receptors for Advanced Glycation End-Products (RAGE) Diminishes Acute Secondhand Smoke-Induced Inflammation in Mice, Tyler Thomas Wood

Theses/Dissertations from 2013

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FGF4 Induced Wnt5a Gradient in the Limb Bud Mediates Mesenchymal Cell Directed Migration and Division, John C. Allen

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Involvement of AMPK and AP-1 Biochemical Pathways in IL-6 Regulation of Steroidogenic Enzymes in the Adrenal Cortex, Matharage Shenali De Silva

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Susceptibility of Apoptotic Cells to Hydrolysis by sPLA2: Molecular Basis and Mechanisms Defined, Elizabeth Gibbons

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Beta-Amyloid Inhibition of Alpha 7 Nicotinic Acetylcholine Receptors and Factors That Potentially Influence the Aβ/nAChR Interaction, Christopher L. Jacobsen

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A Model for Sensory Neuron Development by FGF and Notch: A Multifactorial Approach, Jacob Eugene Voelkel

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Endocannabinoid-Dependent Long-Term Depression of Ventral Tegmental Area GABA Neurons, Jared Mark Weed

Theses/Dissertations from 2012

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Regulation of Sensory Neurogenesis in the Trigeminal Placode: Notch Pathway Genes, Pax3 Isoforms, and Wnt Ligands, Jason Samuel Adams

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Membrane Properties Involved in Calcium-Stimulated Microparticle Release from the Plasma Membranes of S49 Lymphoma Cells, Lauryl Elizabeth Campbell

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Iron Deficiency Causes a Shift in AMP-Activated Protein Kinase (AMPK) Catalytic Subunit Composition in Rat Skeletal Muscle, John Merrill

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The Pro-Inflammatory Contributions of Receptors for Advanced Glycation End-Products (RAGE) in Alveolar Macrophages Following Cigarette Smoke Exposure, Adam Benjamin Robinson

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Long-Term Depression of Excitatory Inputs to GABAergic Neurons in the Ventral Tegmental Area, Philip J. Sandoval

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Tissue Specific Porcupine Deletion Reveals a Novel Role for Ectodermal Wnts in Musculotendon Development, Aaron P. Smith

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Characterization of Altered Epithelial Cell Turnover and Differentiation in Embryonic Murine Lungs That Over-Express Receptors for Advanced Glycation End-Products (RAGE), Jeffrey Alan Stogsdill

Theses/Dissertations from 2011

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The Effects of β-Amyloid on α7 Nicotinic Acetylcholine Receptors Expressed in Xenopus Oocytes, Malia L. Anderson

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Role of Wnt5a and Possible Pathway of Action Through Ror2 in Proximodistal Outgrowth of the Limb, Tiffanie M. Dahl

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Possible Molecular Mechanism to Account for Wavelength Dependence of Equilibration Rates of Patman and Laurdan in Phosphatidylcholine Bilayers, Hannabeth A. Franchino

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Calcineurin is Required for TRPV1-induced LTD of CA1 Stratum Radiatum Interneurons, Tyron DeRay Jensen

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Mechanisms of Prenatal High-Salt "Fetal Programming" Resulting in Stress Hyperresponsiveness in The Adult Female Offspring in The Sprague Dawley Rat., Clinton L. Johnson

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c-Met Initiates Epithelial Scattering through Transient Calcium Influxes and NFAT-Dependent Gene Transcription, Peter R. Langford

Theses/Dissertations from 2010

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Anti-Depressive and Anti-Obesity Changes Following Either Dietary Isoflavone Treatment or Injection Treatment with the Isoflavonoid Equol: Positive Response Dependent on Animal Age and Ovarian Status in Female Long Evans Rats, Crystal Blake

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Liver Kinase B1/AMP-Activated Protein Kinase Signaling in the Diaphragm, Jacob D. Brown

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Role of AMPK in the Upregulation of Steroidogenic Acute Regulatory Protein in the Zona Fasciculata of the Adrenal Cortex, Adam Wesley Dayton

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Chronic AMP-Activated Protein Kinase Activation and a High-Fat Diet Have an Additive Effect on Mitochondria in Rat Skeletal Muscle, Natasha Fillmore

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Proteoliposome Proton Flux Assays Establish Net Conductance, pH-Sensitivity, and Functional Integrity of a Novel Truncate of the M2 Ion "Channel" of Influenza A, Emily Peterson

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Characterization of the LKB1-MO25-STRAD AMPKK Complex in Adult Mouse Skeletal Muscle, Cody Don Smith

Theses/Dissertations from 2009

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Function of the Notch/Delta Pathway in Ophthalmic Trigeminal Placode Development, Matthew K. Ball

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Molecular and Cellular Mechanisms Whereby the Apical Ectodermal Ridge (AER), Via Wnt5a, Mediates Directional Migration of the Adjacent Mesenchyme During Vertebrate Limb Development, Kate E. Kmetzsch

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Zyxin Regulates Epithelial-Mesenchymal Transition by Mediating Actin-Membrane Linkages at Cell-Cell Junctions, Liv Rebecca Sperry

Theses/Dissertations from 2008

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Mechanisms by Which Apoptotic Membranes Become Susceptible to Secretory Phospholipase A2, Rachel Williams Bailey

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Wnt5a Signaling Independently of the Planar Cell Polarity Pathway Resulting in Convergent Extension and Neural Tube Closure During Vertebrate Development, Jared James Barrott

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The Effects of Prenatally Administered Phytoestrogens on the Reproductive and Behavioral Development of Long-Evans Rats, Crystal Blake

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The Effects of a Resveratrol Derivative on Regulatory Behaviors and Reproductive Health in Male and Female Long-Evans Rats, Kimberly Michelle Fabick

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Differential Expression and Functional Characterization of Alpha3 Beta2 Neuronal Nicotinic Acetylcholine Receptors, John Hideo Mizukawa

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The Effects of Excess Corticosterone on LKB1 and AMPK Signaling in Skeletal Muscle of Rats, Gary N. Nakken

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Investigating and Modeling Possible Mechanisms by Which Healthy Cell Membranes Become Resistant to Hydrolysis by Secretory Phospholipase A2, Jennifer Nelson

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A Comparative Analysis of Hydrolysis Kinetics by sPLA2 Isoforms During Apoptosis in S49 Cells, Erin Dalene Olson

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Cellular and Matrix Changes in Articular Cartilage of the Disproportionate micromelia Mouse Model of Osteoarthritis, Crystal Noelle Smaldone

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Determining the Role of Wnt5a Signaling in Embryonic Limb Outgrowth via Clonal Analysis, Whitney Herrod Sowby

Theses/Dissertations from 2007

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Regulation of LKB1-STRAD-MO25 Complex Expression and Activation of AMPK in Skeletal Muscle by Thyroid Hormone, Devon Jack Branvold

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Effects of Endurance Training on the AMPK Response to Exercise., David Gerald Chesser

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AMP-activated protein kinase kinase activity and phosphorylation of AMP-activated protein kinase in contracting muscle of sedentary and endurance trained rats, Denise Hurst

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Maternal High-Salt Diet During Pregnancy in Sprague Dawley Rats Programs Exaggerated Stress-Induced Blood Pressure and Heart Rate Responses in Adult Female Offspring, Summer Hayes King

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Regulation of Adrenal Steroidogenesis by Interleukin-6, Stephen A. McIlmoil

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The Role of STAT and the Jak/STAT Pathway In Mediating the Effects of Interleukin-6 on StAR Expression, Janae Strickland

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Thermodynamic Evidence That Ganglioside-Mediated Insertion Of Botulinum A Into The Cholinergic Nerve Ending May Precede Endocytosis And Acidification: A Langmuir Film Study, Bradley Adam Strongin

Theses/Dissertations from 2006

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Construction of a COL11A1 Transgene Vector, Cameron McKell Beck

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The Role of Pax3 in Neuronal Differentiation of the Ophthalmic (OpV) Trigeminal Placode and Neural Tube during Chicken Embryonic Development, James R. Bradshaw

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The Effects of 3-Phosphoglycerate and Other Metabolites on the Activation of AMP-Activated Protein Kinase by LKB1/STRAD/MO25, William John Ellingson

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The Influence of Membrane Lipid Order on Cell Shape and Microvesiculation in Human Erythrocytes, Laurie Jackson Gonzalez

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PKA as an Upstream Kinase for LKB1/STRAD/MO25, Seth Taylor Herway

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The Role of Wnt Signaling in Development of the Ophthalmic Trigeminal Placode., Rhonda Nicole Lassiter

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Fgf4 and Wnt5a/Pcp Signaling Promote Limb Outgrowth by Polarizing Limb Mesenchyme, Keri Lynn Low

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Properties of Conductance and Inhibition of Proton Channels: M2 from Influenza A Virus and Fo from Escherichia coli ATP Synthase, Jeffrey C. Moffat

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The Role of FGFR4 in Trigeminal Placode Cell Development, Stephanie Beth Reynolds

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Expression and Function of Alpha3 and Beta2 Neuronal Nicotinic Acetylcholine Receptor Subunits in HEK-293 Cells, Nathan W. Steinhafel

Theses/Dissertations from 2004

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Mechanism Governing the Cellular Susceptibility to Secretory Phospholipase A2, Lauren Blackburn Jensen

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Phosphorylation of Skeletal Muscle Acetyl-CoA Carboxylase by AMPK Enhances Palmitoyl-CoA Inhibition, Dustin S. Rubink