Effects of Acute Injections of EtOH in Cytokine Release in Mice

Authors

Alina Svitlana Rodriguez Bezruchko, Brigham Young UniversityFollow
Alka Gaur, Brigham Young University
Carlos M. Moreno, Brigham Young University
Jordan T. Yorgason, Brigham Young University
Scott Weber, Brigham Young University - ProvoFollow

Files

Keywords

Alcohol, cytokines, addiction

Abstract

To learn the pathway by which the peripheral immune system interacts with dopaminergic neurons and triggers an addiction response, we compared cytokine and chemokine production levels before and after a 20-minute ethanol injection. Since some cytokines and chemokines can cross the blood-brain barrier, their peripheral production may influence neural activity. We had four groups: ethanol, saline, domperidone-ethanol, and domperidone-saline. As domperidone is a dopamine antagonist, we will use it as a control to verify that the change in cytokine production is due to ethanol rather than other factors.

BYU ScholarsArchive Citation

Rodriguez Bezruchko, Alina Svitlana; Gaur, Alka; Moreno, Carlos M.; Yorgason, Jordan T.; and Weber, Scott, "Effects of Acute Injections of EtOH in Cytokine Release in Mice" (2025). Library/Life Sciences Undergraduate Poster Competition 2025. 59.
https://scholarsarchive.byu.edu/library_studentposters_2025/59

Document Type

Article

Publication Date

2025

Language

English

College

Life Sciences

Department

Microbiology and Molecular Biology

University Standing at Time of Publication

Senior

Copyright Use Information

https://lib.byu.edu/about/copyright/