Neuroimmune effects of methamphetamine and ethanol in the nucleus accumbens

Authors

Brayden Parker, Brigham Young University - ProvoFollow
Derek Langford, Brigham Young University - Provo
Channing Syme, Brigham Young University - Provo
Chris Galbraith, Brigham Young University - Provo
Savannah Evans, Brigham Young University - Provo
Matthew Burris, Brigham Young University - Provo
Jordan T. Yorgason, Brigham Young University - ProvoFollow

Files

Keywords

Microglial activation, methamphetamine, ethanol, ROS

Abstract

• Microglia are the innate immune cells of the brain and change morphology with activation, with increased ameoboid morphology with increased immune activation.
• Microglia release and clear reactive oxygen species (ROS)
• ATP is a known chemoattractant to microglia and is released at dopamine terminals in the nucleus accumbens (NAc), which is a reward center of the brain
• Methamphetamine (Meth) is a psychostimulant drug that decreases dopamine clearance and increases ROS

BYU ScholarsArchive Citation

Parker, Brayden; Langford, Derek; Syme, Channing; Galbraith, Chris; Evans, Savannah; Burris, Matthew; and Yorgason, Jordan T., "Neuroimmune effects of methamphetamine and ethanol in the nucleus accumbens" (2025). Library/Life Sciences Undergraduate Poster Competition 2025. 24.
https://scholarsarchive.byu.edu/library_studentposters_2025/24

Document Type

Book

Publication Date

2025

Language

English

College

Life Sciences

Department

Cell Biology and Physiology

University Standing at Time of Publication

Junior

Copyright Use Information

https://lib.byu.edu/about/copyright/