Understanding The Impact of Post-Translational Modifications on Nucleosome Positioning

Authors

Bronwyn Kennington-Nitz, Brigham Young University - ProvoFollow
Steven Johnson, Brigham Young University - ProvoFollow
Sophie Lo, Brigham Young University - Provo
Michael Mann, Brigham Young University - Provo
David Bates, Brigham Young University - Provo

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Keywords

H3, acetyl-lysine, nucleosome, histone

Abstract

The placement of histones along DNA is known to be a significant factor in determining gene expression in eukaryotic cells, with post-translational modifications (or PTMs) helping modulate gene expression by acting as an intermediate to other factors. Using the Lys>Gln and Acetyl-Lys mutations of H3, our working hypothesis is that acetylation will decrease the overall strength of positioning, and that mutations will have an identical or nearly identical effect on nucleosome positioning.

BYU ScholarsArchive Citation

Kennington-Nitz, Bronwyn; Johnson, Steven; Lo, Sophie; Mann, Michael; and Bates, David, "Understanding The Impact of Post-Translational Modifications on Nucleosome Positioning" (2024). Library/Life Sciences Undergraduate Poster Competition 2024. 9.
https://scholarsarchive.byu.edu/library_studentposters_2024/9

Document Type

Poster

Publication Date

2024-03-21

Language

English

College

Life Sciences

Department

Microbiology and Molecular Biology

University Standing at Time of Publication

Junior

Copyright Use Information

https://lib.byu.edu/about/copyright/