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Keywords

Cancer, immunology, tumor microenvironment, cell biology, lung

Abstract

Lung cancer is the leading cause of cancer related death in the United States, and non-small cell (NSCLC) is the most common type. An increasingly prevalent treatment in the last few years for NSCLC has been immunotherapy. However, for immunotherapy to be the most effective, we need to have a better understanding of how the immune system interacts with cancer in all stages. Specifically, we need to know where the immune cells reside, how they interact with each other, and how these populations change as the disease progresses. To define the tumor microenvironment, we stained 27 whole tumor slides with a panel of 7 markers and identified the spatial distribution of immune cell types around the tumor. We then compared that information across stages to see how it changed over time.

Document Type

Poster

Publication Date

2024-03-21

Language

English

College

Life Sciences

Department

Microbiology and Molecular Biology

University Standing at Time of Publication

Junior

The Changing Tumor Microenvironment of Non-Small Cell Lung Cancer

Included in

Microbiology Commons

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