Estradiol effects on dopamine release and cholinergic interactions
Neurons, neuroscience, dopamine, estradiol
Dopamine release in the striatum is regulated by intrinsic activity as well as local cholinergic interneurons. Dopamine terminals express nicotinic acetylcholine receptors (nAChR), including a4~2 receptors that are sensitive to sex hormones. These receptors are also activated by acetylcholine release from cholinergic interneutons that is sufficient for driving dopamine relelase independent on dopamine somatic firing. The present study examines cholinergic mediated dopamine release and the sex hormone estradiol.
BYU ScholarsArchive Citation
Carroll, Joseph; Perkins, Marcus; Cook, Whitney; Busselburg, Laird; Brady, Lillian; Calipari, Erin; Estrada, Zak; and Yorgason, Jordan T., "Estradiol effects on dopamine release and cholinergic interactions" (2022). Library/Life Sciences Undergraduate Poster Competition 2022. 12.
Cell Biology and Physiology
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