Title

Folate and Inflammatory Markers Moderate the Association Between Helicobacter pylori Exposure and Cognitive Function in US Adults

Keywords

Helicobacter pylori, cognition, inflammation folate, C‐reactive protein, ferritin

Abstract

Helicobacter pylori is a gram‐negative bacterium found in the stomach and upper gastrointestinal tract of a significant portion of the worldwide population 1. Infection occurs primarily through ingestion but may also occur in utero 2. Helicobacter pylori locates to less acidic portions of the mucosal lining of the gastrointestinal tract ensuring long‐term persistence within the host. Gastritis typically follows the initial infection and inflammation persists until successful treatment 3. Genomic studies have described a specific strain of H. pylori that expresses the cagA protein, which can trigger a robust inflammatory response 4.

Original Publication Citation

Berrett, Andrew N., Shawn D. Gale, Lance D. Erickson, Bruce Brown, and Dawson W. Hedges. (2016). “Folate and inflammatory markers moderate the association between Helicobacter pylori exposure and cognitive function in U.S. adults.” Helicobacter. 21(6):471-480. DOI: 10.1111/hel.12303.

Document Type

Peer-Reviewed Article

Publication Date

2016-03-03

Publisher

Helicobacter

Language

English

College

Family, Home, and Social Sciences

Department

Sociology

University Standing at Time of Publication

Associate Professor

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