Folate and Inflammatory Markers Moderate the Association Between Helicobacter pylori Exposure and Cognitive Function in US Adults
Helicobacter pylori, cognition, inflammation folate, C‐reactive protein, ferritin
Helicobacter pylori is a gram‐negative bacterium found in the stomach and upper gastrointestinal tract of a significant portion of the worldwide population 1. Infection occurs primarily through ingestion but may also occur in utero 2. Helicobacter pylori locates to less acidic portions of the mucosal lining of the gastrointestinal tract ensuring long‐term persistence within the host. Gastritis typically follows the initial infection and inflammation persists until successful treatment 3. Genomic studies have described a specific strain of H. pylori that expresses the cagA protein, which can trigger a robust inflammatory response 4.
Original Publication Citation
Berrett, Andrew N., Shawn D. Gale, Lance D. Erickson, Bruce Brown, and Dawson W. Hedges. (2016). “Folate and inflammatory markers moderate the association between Helicobacter pylori exposure and cognitive function in U.S. adults.” Helicobacter. 21(6):471-480. DOI: 10.1111/hel.12303.
BYU ScholarsArchive Citation
Berrett, Andrew; Gale, Shawn D.; Erickson, Lance; Brown, Bruce L.; and Hedges, Dawson W., "Folate and Inflammatory Markers Moderate the Association Between Helicobacter pylori Exposure and Cognitive Function in US Adults" (2016). Faculty Publications. 2762.
Family, Home, and Social Sciences
© 2016 John Wiley & Sons Ltd