Objectives. Evaluate C-reactive protein (CRP) levels according to weight and physical activity. The study explored how changes in CRP were associated with baseline CRP, weight, and physical activity and changes in these variables.
Methods. A randomized controlled study design assigned 348 individuals to the intervention or control group with measurements taken at baseline, 6 weeks, and 6 months of body weight, physical activity, and serum CRP levels. Participants attended an intensive 40-hour educational course delivered over a four-week period.
Results. At baseline, CRP was negatively associated with total steps/week, and positively associated with weight, BMI, percent fat, and saturated fat at baseline. CRP significantly decreased through 6 weeks and also through 6 months for only those with high CRP at baseline. For those with high CRP at baseline, the decrease was significant for normal, overweight, and obese groups of people. Changes in weight or physical activity were not significantly associated with changes in CRP.
Conclusions. Over 6 week and 6 month follow-up periods, the intervention failed to discriminate changes in CRP. Changes in CRP were only associated with baseline levels of CRP and BMI and were not associated with changes in any of the selected variables considered.
College and Department
Life Sciences; Exercise Sciences
BYU ScholarsArchive Citation
Massey, Michael T., "C-reactive Protein Levels According to Physical Activity and Body Weight for Participants in the Coronary Health Improvement Project" (2007). All Theses and Dissertations. 929.
C-reactive protein (CRP), physical activity, body weight, percent body fat, saturated fat, body mass index (BMI), Coronary Health Improvement Project (CHIP)