I. An isothermal titration microcalorimeter having a colume of 4 ml and capable of temerature control to ±2 x 10-5°C is described. Major components include a constant temperature water bath controlled to ±3 x 10-4°C, a platinum reation vessel, and an isothermal control circuit consisting of constant Peltier thermoelectric cooling and variable Joule heating controlled by a thermistor in an AC Wheatstone bridge circuit. The calorimeter was tested by measuring the heat of ionization of water and was found to produce data accurate to ± 0.1% where small samples are used such as in the investigation of many biological systems.
College and Department
Chemistry and Biochemistry
BYU ScholarsArchive Citation
Gardner, John Willard, "I. An isothermal titration microcalorimeter. II. Importance of micronutrients in nutrition. III. Zinc bibliography" (1973). Theses and Dissertations. 8210.
Volumetric analysis, Calorimetry, Trace elements in nutrition, Nutrition, Zinc, Bibliography