The discovery of a substance in rice polishings that was useful in preventing beriberi was first shown by Grijns and Vedder (Wuest, 1962). In 1926, Jansen and Donath (Wuest, 1962} crystallized this substance which was subsequently synthesized independently by Williams and Cline (1936} and Grewe (1936). This substance was named thiamine by Williams (1936) because of its structure having the vital thiazole ring and because it was an "essential amine."
College and Department
Plant and Wildlife Sciences
BYU ScholarsArchive Citation
Bitter, Ronald Adams, "The effects of force feeding on the levels of pyruvate, glucocorticoids and glucose in the blood and on adrenal weight in thiamine-deprived and thiamine-antagonized rats" (1968). Theses and Dissertations. 7630.
Vitamins; Metabolism; Vitamin therapy