Cowden hamartoma tumor syndrome, genetic testing, hereditary cancer syndrome, Li-Fraumeni syndrome, Peutz-Jeghers syndrome, primary care nurse practitioner
Hereditary cancer syndromes, resulting from mutations of tumor-suppressor genes, can significantly increase risk for breast cancer. While Hereditary Breast and Ovarian Cancer Syndrome caused by BRCA1/2 mutations is well known, less well-known hereditary cancer syndromes also exist. This clinical practice feature focuses on three other syndromes including, Li-Fraumeni, Cowden, and Peutz-Jeghers. This article will help prepare nurse practitioners to recognize key features of these syndromes and understand testing criteria. Additionally, this article discusses barriers to diagnosing hereditary cancer syndromes and the role of primary care nurse practitioners in ordering genetic tests and making genetic referrals for optimal patient care.
BYU ScholarsArchive Citation
Shuman, Hanford and Himes, Deborah, "Hereditary Cancer Syndrome Recognition and Testing for the Primary Care Nurse Practitioner: Beyond BRCA" (2020). Student Works. 294.
© 2020 Elsevier Inc. All rights reserved. This is the author's submitted version of this article. The definitive version can be found at https://www.npjournal.org/article/S1555-4155(20)30175-6/fulltext
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