A different dimension: a comparison between 2D cell lines and 3D organoids in cancer drug screening cell viability​

Authors

Payton Curran, Brigham Young UniversityFollow
Isaac Packer, Brigham Young University
DeLaney Anderson, Brigham Young University
VIctoria Johnson, Brigham Young University
Jeffery Okojie, Brigham Young University
Jared Barrott, Brigham Young University - ProvoFollow

Files

Keywords

Cancer, Drug, 2D cells vs. 3D organioids

Abstract

Cancer drug screening is commonly performed on two-dimensional (2D) cancer cell lines. Recent innovations in cell line development and methods of incubation has led to further interest in the development of three-dimensional (3D) organoids from standard cancer cell lines and patient-derived tissue. Our research intends to test the relationship between cell viability of 2D cancer cell lines and the viability of 3D organoids during cancer drug screening.

BYU ScholarsArchive Citation

Curran, Payton; Packer, Isaac; Anderson, DeLaney; Johnson, VIctoria; Okojie, Jeffery; and Barrott, Jared, "A different dimension: a comparison between 2D cell lines and 3D organoids in cancer drug screening cell viability​" (2025). Library/Life Sciences Undergraduate Poster Competition 2025. 74.
https://scholarsarchive.byu.edu/library_studentposters_2025/74

Document Type

Book

Publication Date

2025

Language

English

College

Life Sciences

Department

Cell Biology and Physiology

University Standing at Time of Publication

Junior

Copyright Use Information

https://lib.byu.edu/about/copyright/