Engineering Chromoprotein Variants With New Colors

Authors

Anna Bowman, Brigham Young UniversityFollow
Joel S. Griffitts, Brigham Young University - ProvoFollow
Kyler Fullmer, Brigham Young University

Files

Keywords

Chromoprotein, Color, Chromophore, Mutagenesis, Variant

Description

Chromoproteins are naturally occurring proteins that exhibit distinct colors due to their chromophore- a conserved tripeptide sequence that absorbs light. The protein folds into a beta-barrel structure, with the chromophore embedded at the base of an alpha-helix within the barrels core. Originally derived from marine organisms, the expression of chromoproteins have been studied to understand the importance of their structural properties. Hypothesis: Modifying the amino acid resides within proximity of the chromophore in chromoproteins on the primary sequence will alter the environment of the chromophore, leading to a change in color. By randomizing these residues, we expect to make chromoprotein variants.

BYU ScholarsArchive Citation

Bowman, Anna; Griffitts, Joel S.; and Fullmer, Kyler, "Engineering Chromoprotein Variants With New Colors" (2025). Library/Life Sciences Undergraduate Poster Competition 2025. 53.
https://scholarsarchive.byu.edu/library_studentposters_2025/53

Document Type

Article

Publication Date

2025

Language

English

College

Life Sciences

Department

Microbiology and Molecular Biology

University Standing at Time of Publication

Junior

Copyright Use Information

https://lib.byu.edu/about/copyright/