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multiple sclerosis, immunocompromised, tight junction
- Multiple Sclerosis (MS) is a debilitating neurological and autoimmune disease in which immune cells cause demyelination of axons in nervous tissue.
- Current treatments for the disease are principally aimed at weakening the immune system to therefore weaken the autoimmune attack on the brain. This leaves patients prone to other sicknesses.
- We seek a treatment that prevents the immune cells from entering the central nervous system (CNS) thereby protecting its cells.
- We can prevent immune cells from entering the CNS by strengthening the blood brain barrier through targeting claudin 5 proteins in the tight junctions.
- This new treatment could mean increased health and peace of mind for MS patients undergoing treatment.
BYU ScholarsArchive Citation
Helquist, Carter and Mizrachi, Dario, "New treatment for multiple sclerosis could halt disease progression without weakening immune system" (2022). Library/Life Sciences Undergraduate Poster Competition 2022. 56.
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