BYU ScholarsArchive

Title

EEG as Successful Diagnostic Tool for Immune Effector Cell Associated Neurotoxicity Syndrome

Authors

Daniel Jones, Brigham Young University - ProvoFollow
Christine Eckhardt, Massachusetts General Hospital
Haoqi Sun, Massachusetts General Hospital
Ryan Tesh, Massachusetts General Hospital
Brandon Westover, Massachusetts General Hospital

Files

Keywords

Neurology, Machine Learning, Medicine, Cancer, Brain

Abstract

CAR T cell therapy was first proven effective in 2013¹ for the treatment of certain cancer s . However, its widespread adoption is still hindered by side effects like immune effector cell associated neurotoxicity syndrome (ICANS). Current research aims to better predict, diagnose, and treat ICANS so that CAR T cell therapy can be more widely applied. Although prior studies have attempted to identify an objective biomarker of ICANS² , current practice relies on clinical assessment to diagnose ICANS. We hypothesize that qualitative features of the EEG may be utilized to develop a physiological grading system of the severity of ICANS.

BYU ScholarsArchive Citation

Jones, Daniel; Eckhardt, Christine; Sun, Haoqi; Tesh, Ryan; and Westover, Brandon, "EEG as Successful Diagnostic Tool for Immune Effector Cell Associated Neurotoxicity Syndrome" (2022). Library/Life Sciences Undergraduate Poster Competition 2022. 55.
https://scholarsarchive.byu.edu/library_studentposters_2022/55

Document Type

Poster

Publication Date

2022-3

Language

English

College

Life Sciences

Department

Computer Science

University Standing at Time of Publication

Junior

Copyright Use Information

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