Tumor cells can erase the effects of duplicated and deleted chromosomes

Title

Tumor cells can erase the effects of duplicated and deleted chromosomes

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Keywords

bioinformatics, genetics, proteomics, copy number, survival

Abstract

In most cancers, tumor cells frequently delete some chromosomes and duplicate others. This is called copy number variation (CNV). Normally, we expect deletions to cause decreases in protein production, and duplications to cause increases. To see if this is what happens in cancer, we identified common CNVs and studied their effects on protein production and patient survival.

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Document Type

Poster

Publication Date

2022-3

Language

English

College

Life Sciences

Department

Biology

University Standing at Time of Publication

Senior

Tumor cells can erase the effects of duplicated and deleted chromosomes

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