Tumor cells can erase the effects of duplicated and deleted chromosomes
bioinformatics, genetics, proteomics, copy number, survival
In most cancers, tumor cells frequently delete some chromosomes and duplicate others. This is called copy number variation (CNV). Normally, we expect deletions to cause decreases in protein production, and duplications to cause increases. To see if this is what happens in cancer, we identified common CNVs and studied their effects on protein production and patient survival.
BYU ScholarsArchive Citation
Lindgren, Caleb; Minor, Chelsie; and Payne, Samuel, "Tumor cells can erase the effects of duplicated and deleted chromosomes" (2022). Library/Life Sciences Undergraduate Poster Competition 2022. 52.
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