BYU ScholarsArchive

Title

P39 Effects on Accumbal DA in Young vs. Old Mice

Authors

Serin Lee, Brigham Young University
Jared Mcfarlane, Brigham Young University
Hannah Brundage, Brigham Young UniversityFollow
Jordan Yorgason, Brigham Young University

Files

Keywords

Dopamine, Aging, AMPK pathway, ZMP

Abstract

Dopamine (DA) release decreases in the nucleus accumbens (NAc)with age, which has been linked to neurodegenerative conditions. ZMP acts as an endogenous activator of AMPK which is correlated to increased DA signalling. P39, exogenous ZMP, also activates the AMPK pathway necessary for DA release. The objective of this study was to examine if the presence of P39 restored these depleted levels of DA in aged mice.

BYU ScholarsArchive Citation

Lee, Serin; Mcfarlane, Jared; Brundage, Hannah; and Yorgason, Jordan, "P39 Effects on Accumbal DA in Young vs. Old Mice" (2022). Library/Life Sciences Undergraduate Poster Competition 2022. 5.
https://scholarsarchive.byu.edu/library_studentposters_2022/5

Document Type

Poster

Publication Date

2022-3

Language

English

College

Life Sciences

Department

Cell Biology and Physiology

University Standing at Time of Publication

Sophomore

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