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Keywords

rheumatic heart disease, inflammatory heart disease, Oceania, Samoa, immune response genes, toll-like receptor, TLR, bacterial flagella

Abstract

Rheumatic heart disease is an inflammatory heart disease that affects millions of people around the world. Especially high rates of the disease can be found in Oceania, including the island nation of Samoa. Genetic studies of immune response genes have provided insight into a possible genetic link to increased susceptibility to rheumatic heart disease, including the genes that code for the toll-like receptor (TLR) protein family. One of the functions of TLR proteins is to recognize the presence of bacteria via identification of bacterial flagella.

Document Type

Poster

Publication Date

2019-04-05

Language

English

College

Life Sciences

Department

Biology

Genetic Basis for Elevated Rheumatic Heart Disease Susceptibility

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