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Journal of Undergraduate Research

Keywords

t cell immunotheraphy, infection disease, cancer

College

Life Sciences

Department

Biology

Abstract

This project was focused on improving the immune response to infectious disease and cancer. We have engineered T cell receptors with 1000-fold increase in affinity and will characterize their value as diagnostics and therapeutics. In addition, we examined changes in T cell function due to the co-receptor CD5. We also examined how T cell responses to infection are dependent upon metabolic and epigenetic regulation.

Included in

Biology Commons

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