Cell Free Single Stranded DNA Concentration in CSF as biomarker to diagnose Alzheimer’s Disease

Authors

Taylor Avei, Brigham Young University
Dr. John Kauwe, Brigham Young University

Keywords

DNA concentration, CSF, alzheimer's disease

College

Life Sciences

Department

Biology

Abstract

The neuropathology of Alzheimer’s Disease (AD) is well-known as a degradation of neural connections in the brain caused by multiple deposits of Amyloid-beta peptide plaques as well as neurofibrillary tangles of tau proteins [1]. Because of this and successful research, both Amyloid-beta 42 and tau protein levels in cerebrospinal fluid currently serve as important biomarkers for the diagnosis of AD according to the New Research Criteria for the Diagnosis of AD provided by the International Working Group (IWG) [2].

Recommended Citation

Avei, Taylor and Kauwe, Dr. John (2019) "Cell Free Single Stranded DNA Concentration in CSF as biomarker to diagnose Alzheimer’s Disease," Journal of Undergraduate Research: Vol. 2019: Iss. 2019, Article 109.
Available at: https://scholarsarchive.byu.edu/jur/vol2019/iss2019/109