Journal of Undergraduate Research


beta cell mass, Nr4a3, vitro phenotypes Nr4a3 KO mouse


Life Sciences


Nutrition, Dietetics, and Food Science


The academic objectives of this Mentoring Environment Grant (MEG) were to 1) train undergraduate students in the scientific process to prepare them in careers as physicians and scientists, and 2) to determine if the in vitro phenotypes observed in Nr4a3 deficient beta cell lines are translatable to the Nr4a3 KO mouse. . We were successful in accomplishing these objectives, as evidenced by the training of four undergraduate students, presentation of research and local and national meetings, and initial preparation of a manuscript reporting our findings. While we did have difficulty breeding these mice, this study gives us the basis of data to begin a second round of studies.

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