Journal of Undergraduate Research
Keywords
inflammation in the eye, mechanical stress, osteoarthritis, metabolic syndrome
College
Life Sciences
Department
Physiology and Developmental Biology
Abstract
A correlation between Osteoarthritis (OA), affecting over 27 million people in the US [1], and metabolic syndrome (MS), affecting over 340 million people worldwide [2], becomes strikingly important as the search for an effective treatment for OA continues. Increasing evidence has shown that OA is linked to systemic inflammation and MS. With MS comes other substantial comorbidities, including diabetic retinopathy (DR). Ocular inflammation promoted through mechanically induced OA would provide evidence that mechanical stress can be a factor leading to systemic inflammation. Such results would have profound impacts upon the way we view OA as a metabolic disorder, leading to novel treatments for OA and perhaps other diseases.
Recommended Citation
Goodman, Michael and Kooyman, David
(2018)
"“Seeing” Beyond the Knees: Inflammation in the Eye as a Result of Mechanical Stress,"
Journal of Undergraduate Research: Vol. 2018:
Iss.
1, Article 168.
Available at:
https://scholarsarchive.byu.edu/jur/vol2018/iss1/168