Elucidating the Role of the Transcriptional Co-activator camta1 in Cardiac Development

Authors

Nate Batey, Brigham Young University
Zach Frederich, Brigham Young University
Morgan Fronk, Brigham Young University
Nate Jenkins, Brigham Young University
Jonathon Hill, Brigham Young University

Keywords

transcriptional co-activator camta1, cardiac development, congenital heart disease, CHD

College

Life Sciences

Department

Physiology and Developmental Biology

Abstract

Congenital Heart Disease (CHD) is the most common type of birth defect in the United States, causing more first-year infant deaths than any other birth defect (1). While the causes of CHD are varied, genetic defects are known to play a significant role. Identifying and studying genes involved in embryonic heart development can enhance understanding of the genetic factors in CHDs. The camta1 gene is a promising candidate due to its transient expression in heart morphogenesis and its relationship to camta2 , the only other member of its family in vertebrates and a known player in adult heart failure (2,3).

Recommended Citation

Batey, Nate; Frederich, Zach; Fronk, Morgan; Jenkins, Nate; and Hill, Jonathon (2018) "Elucidating the Role of the Transcriptional Co-activator camta1 in Cardiac Development," Journal of Undergraduate Research: Vol. 2018: Iss. 1, Article 167.
Available at: https://scholarsarchive.byu.edu/jur/vol2018/iss1/167