Journal of Undergraduate Research


accumulation and retention in brain, supplemental selenium, dietary composition


Life Sciences


Nutrition, Dietetics, and Food Science


It is estimated that over 6 million Americans suffer from the neurodegenerative diseases of Alzheimer’s and Parkinson’s combined, with 1 in 4 Americans suffering from some type of mental illness (1). Oxidative damage and inflammation, which is a recognized hallmark of neurodegenerative diseases, can be prevented by antioxidant enzymes such as glutathione peroxidase whose key component is selenium and which relies on a selenium delivering protein called selenoprotein P (2). Since neurodegeneration that affects so many people can potentially be avoided by understanding how selenium is accumulated in and delivered to body tissue, understanding how and where selenium is accumulated in body tissue is of great importance.

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