The Effect of the Overexpression of IRF% in B-Cells on Inflammatory and Co-Stimulatory Activity

Authors

Reika Takita, Brigham Young University
Brian Poole, Brigham Young University

Keywords

overexpression of IRF%, B-cells, inflammation, co-stimulatory activity

College

Life Sciences

Department

Microbiology and Molecular Biology

Abstract

Systemic Lupus Erythematosus is a chronic autoimmune disease characterized by inflammatory tissue damage inflicted by the body's rogue immune system (1). Although treatment is available for the disease, the pathogenesis of SLE remains unclear (2). However, researchers suspect the disease to be associated with environmental, genetic, and hormonal factors (1).

Recommended Citation

Takita, Reika and Poole, Brian (2018) "The Effect of the Overexpression of IRF% in B-Cells on Inflammatory and Co-Stimulatory Activity," Journal of Undergraduate Research: Vol. 2018: Iss. 1, Article 149.
Available at: https://scholarsarchive.byu.edu/jur/vol2018/iss1/149