Journal of Undergraduate Research


RAB10, Alzheimer's disease, brain disorder, prevention


Life Sciences




Alzheimer’s disease is a brain disorder caused by an irreversible degeneration of nerve cells. It is developed in response to a growth of proteins, tau tangles or amyloid plaques, which disrupt communication between neurons in the brain. Because the nerve cells no longer function, they die. It is estimated that as many as 5.1 million Americans may have Alzheimer’s disease and about one to four family members act as caregivers for each individual with Alzheimer’s disease. Many lives are affected by Alzheimer’s which has driven further and extensive research for solutions. However, despite much effort, the genetics of Alzheimer’s remains largely unknown. Most of what is known about the genetics are not helpful in predicting or diagnosing the disease which only emphasizes that much needed progress in the area of genetics.

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