Journal of Undergraduate Research


open source function, utilizing random field theory, MRI analysis


Family, Home, and Social Sciences




When looking at an MRI scan of the brain one is actually viewing millions of voxels (three dimensional pixels) that represent individual groups of signals produced by the MRI machine. Therefore, each voxel is representative of the brains composition at that point in three dimensional space or metabolic activity (as is the case in functional MRI). These qualities are utilized in research to give anatomically meaningful comparisons of the brain between individual test subjects. Doing so involves the process of mass univariate testing and produces a single statistical value at each voxel representing the univariate test (i.e. a tvalue). However, such an approach to comparing MRI scans creates an issue of multiple comparisons and interpretability.

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