MRI Tissue-based intensity standardization for multi-site neuropsychological outcome studied: Problems and Potential Solutions

Authors

Trevor Huff, Brigham Young University
Erin Bigler, Brigham Young University

Keywords

MRI tissue, multi-site neuropsychological outcome, disorders

College

Family, Home, and Social Sciences

Department

Psychology

Abstract

In this era of the human connectome, automated image analysis techniques, and large scale multi-site neuroimaging databases examining neuropsychological outcome across a broad spectrum of neurological and neuropsychiatric disorders, there is a particular need to address how to combine neuroimaging studies that use different volumetric sequences or Magnetic Resonance Imaging (MRI) studies performed on different platforms. Currently, there is a large volume of studies that utilize data from multiple scanning locations. This data, while important, cannot reliably be used for comparisons without taking into account the various differences that exist between MRI equipment. The purpose of this study is to investigate possible solutions to this existing problem and propose a direction for future investigations.

Recommended Citation

Huff, Trevor and Bigler, Erin (2017) "MRI Tissue-based intensity standardization for multi-site neuropsychological outcome studied: Problems and Potential Solutions," Journal of Undergraduate Research: Vol. 2017: Iss. 1, Article 84.
Available at: https://scholarsarchive.byu.edu/jur/vol2017/iss1/84