Journal of Undergraduate Research
Keywords
sigma receptors, methamphetamine, dopamine release, nucleus accumbens
College
Family, Home, and Social Sciences
Department
Psychology
Abstract
Methamphetamine (METH) is an addictive drug of abuse and METH use is a growing problem in the United States. The current dogma states that psychostimulants such as METH attack the mesocorticolimbic dopamine (DA) system, leading to abnormally high DA release when drugs of abuse are taken (Volkow et al., 2004). A key target area of the mesocorticolimbic system is the nucleus accumbens (NAc). Specifically, DA release in the NAc has been associated with reward and motivation (Oleson et al. 2012).
Recommended Citation
Marchant, Gilbert and Steffensen, Scott
(2017)
"Role of Sigma Receptors in Low-dose Methamphetamine Modulation of Dopamine Release in the Nucleus Accumbens,"
Journal of Undergraduate Research: Vol. 2017:
Iss.
1, Article 79.
Available at:
https://scholarsarchive.byu.edu/jur/vol2017/iss1/79