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Journal of Undergraduate Research

Keywords

bioreacter design, recellularization of whole porcine kidney, kidney failure

College

Ira A. Fulton College of Engineering and Technology

Department

Chemical Engineering

Abstract

Kidney failure affects tens of thousands of individuals annually causing many to rely on dialysis to replace this organ’s function. Most of these individuals are on a waiting list to receive a transplant for years, and unfortunately many die before they are able to reach the top of the list. The bodies of those who do receive kidneys often reject the organs. This rejection can have devastating defects, including mortality. In an effort to change this ongoing cycle we have been researching the idea of creating organs synthesized with the DNA of each specific patient. The process would significantly increase availability of transplant ready organs, and minimize the probability of organ rejection occurrences.

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