The role of LKB1 in Obesity-induced Skeletal Muscle Inflammation and Insulin Resistance

Authors

David Thomson, Brigham Young University

Keywords

LKB1, obesity-induced skeletal muscle inflammation, insulin resistance

College

Life Sciences

Department

Physiology and Developmental Biology

Abstract

The incidence of obesity and the health consequences that accompany it have increased rapidly over the past decade. Understanding the molecular pathways involved in its development will be crucial in developing novel treatment strategies for obesity and associated disorders. Low-grade inflammation likely plays a major role in many of the complications of obesity. We proposed to study the role of liver kinase B1 (LKB1) in the development of inflammation and insulin resistance in obese mice and saturated fatty acid-induced insulin-resistant cells.

Recommended Citation

Thomson, David (2017) "The role of LKB1 in Obesity-induced Skeletal Muscle Inflammation and Insulin Resistance," Journal of Undergraduate Research: Vol. 2017: Iss. 1, Article 333.
Available at: https://scholarsarchive.byu.edu/jur/vol2017/iss1/333