A Phenome Wide Association Study of Multiple Sclerosis and COmorbidities

Authors

Scott Frodsham, Brigham Young University
Mary Davis, Brigham Young University

Keywords

phenome wide association study, multiple sclerosis, comorbidities

College

Life Sciences

Department

Microbiology and Molecular Biology

Abstract

Genome wide association studies (GWAS) have identified relationships between many different genes and diseases. GWAS studies scan whole genomes of many individuals and then associate genetic variants with diseases that the individuals have. In contrast, a phenome wide association study (PheWAS), looks at the phenotypes of many individuals and associates those phenotypes with one or more genetic variants. Electronic medical records (EMRs) linked to DNA biobanks provide both clinical and genetic data of patients. This study utilizes one such EMRlinked DNA biobank called BioVU from Vanderbilt University.

Recommended Citation

Frodsham, Scott and Davis, Mary (2017) "A Phenome Wide Association Study of Multiple Sclerosis and COmorbidities," Journal of Undergraduate Research: Vol. 2017: Iss. 1, Article 215.
Available at: https://scholarsarchive.byu.edu/jur/vol2017/iss1/215