Effect of Methamphetamine on Basal and Phasic Dopamine Release in the Striatum

Authors

Krisana Finlay, Brigham Young University
Scott Steffensen, Brigham Young University

Keywords

methamphetamine, basal and phasic dopamine release, striatum

College

Family, Home, and Social Sciences

Department

Psychology

Abstract

The purpose of this experiment was to determine the action mechanism of the psychostimulant methamphetamine (METH) on basal and phasic dopamine (DA) release in the nucleus accumbens. We investigated METH and its method of action. This was done to better understand the detailed mechanism behind METH and to provide better addiction-solving tools. Previous METH research provided a great starting point, showing a reduction in DA transmission and tyrosine hydroxylase, and increased DA axon and terminal damage, apoptosis (cell death) and axon degeneration.

Recommended Citation

Finlay, Krisana and Steffensen, Scott (2016) "Effect of Methamphetamine on Basal and Phasic Dopamine Release in the Striatum," Journal of Undergraduate Research: Vol. 2016: Iss. 1, Article 72.
Available at: https://scholarsarchive.byu.edu/jur/vol2016/iss1/72