Identification of Location and Timing of ROS Production In Response To Meth Exposure

Authors

Andrew Lamprecht, Brigham Young University
Scott Steffensen, Brigham Young University

Keywords

ROS production, meth exposure, methamphetamine, dopamine

College

Family, Home, and Social Sciences

Department

Psychology

Abstract

Methamphetamine is an extremely addictive drug that acts on the pleasure center of the brain. It causes an increase in the release of dopamine (DA) into the synaptic cleft. This rapid release of DA causes the “rush” felt by drug users. It also causes severe malfunctions in the brain such as anxiety, mood disorders, increased violence, reduced motor skills, impaired verbal learning, and psychosis. Among other things, the cause for these harmful effects could be related to Reactive Oxygen Species (ROS) and their resulting oxidative damage. Oxidative damage has been suggested to constitute early signaling events in programmed cell death, contributing to the idea that it may be the primary source of damage done to the neural tissue from Meth.

Recommended Citation

Lamprecht, Andrew and Steffensen, Scott (2016) "Identification of Location and Timing of ROS Production In Response To Meth Exposure," Journal of Undergraduate Research: Vol. 2016: Iss. 1, Article 69.
Available at: https://scholarsarchive.byu.edu/jur/vol2016/iss1/69