The role of Wnt secretion from Neural Crest Cells in proper craniofacial development

Authors

Bradley Haynes, Brigham Young University
Stark Michael, Brigham Young University

Keywords

Wnt secretion, neural crest cells, craniofacial development

College

Life Sciences

Department

Physiology and Developmental Biology

Abstract

Both Wnt signaling and neural crest cells (NCCs) have a well-established role in the development of facial bones and cartilage. Wnt signaling is known to be required for neural crest cell formation; however, Wnt expression originating from the neural crest after their specification by Wnt1 has not been carefully explored. The purpose of our study is to investigate the role of Wnt secretion from NCCs in craniofacial development. Our hypothesis is that loss of Wnt secretion from NCCs will lead to improper craniofacial development and contribute to facial structure abnormalities.

Recommended Citation

Haynes, Bradley and Michael, Stark (2016) "The role of Wnt secretion from Neural Crest Cells in proper craniofacial development," Journal of Undergraduate Research: Vol. 2016: Iss. 1, Article 182.
Available at: https://scholarsarchive.byu.edu/jur/vol2016/iss1/182