Journal of Undergraduate Research
Keywords
palmitate, upregulating Nr4a1, Nr4a3
College
Life Sciences
Department
Nutrition, Dietetics, and Food Science
Abstract
This project focused on the effects of palmitate on transcription factors, Nr4a1 and Nr4a3. All experiments were preformed on a beta cell line. The first experiment was done to show if palmitate effected proliferation of Nr4a1 and Nr4a3 knockout cell lines. This experiment was preformed adding .2 mmol palmitate to all cells and comparing them to untreated and treated unknocked down cell lines. This showed exactly what was expected which was that proliferation was decreased in Nr4a1 and Nr4a3 knockdown cell lines.
Recommended Citation
Tingey, Jordan and Tessem, Jeffery
(2016)
"This project focused on the effects of palmitate on transcription factors, Nr4a1 and Nr4a3. All experiments were preformed on a beta cell line. The first experiment was done to show if palmitate effected proliferation of Nr4a1 and Nr4a3 knockout cell lines. This experiment was preformed adding .2 mmol palmitate to all cells and comparing them to untreated and treated unknocked down cell lines. This showed exactly what was expected which was that proliferation was decreased in Nr4a1 and Nr4a3 knockdown cell lines.,"
Journal of Undergraduate Research: Vol. 2016:
Iss.
1, Article 170.
Available at:
https://scholarsarchive.byu.edu/jur/vol2016/iss1/170