Journal of Undergraduate Research
Keywords
rs75932628 (R47H), vascular dementia, Cache county
College
Life Sciences
Department
Biology
Abstract
Vascular dementia (VaD) is a neurodegenerative disease caused by atherosclerosis, or inadequate blood flow to the brain as a result of the build-up of fat deposits, dead cells, or other cell debris on the inside of arteries. It shortens the lifespan of those affected, and severely impairs their quality of life. VaD is the second most common form of dementia, after Alzheimer’s disease, accounting for 20-30% of dementia cases. Thus far the risk factors that have been determined are non-specific to the brain: high blood pressure, high cholesterol, and high blood sugar (Roman et. al 2003). There has not been much success targeting genetic variants that increase risk.
Recommended Citation
Sears, Emily and Kauwe, Dr. John
(2016)
"Association of rs75932628 (R47H) with Vascular Dementia in the Cache County Study,"
Journal of Undergraduate Research: Vol. 2016:
Iss.
1, Article 150.
Available at:
https://scholarsarchive.byu.edu/jur/vol2016/iss1/150